SCHEMBL4891028

SCHEMBL4891028

C=CCc1cc[c]s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1631743 0.69
SCHEMBL6292229 0.67 ALDH1A1 (0.34)
SCHEMBL131435 0.65
SCHEMBL15161767 0.64
SCHEMBL743876 0.62
SCHEMBL29660 0.60
Methane SCHEMBL21683042 0.59
SCHEMBL4256977 0.59
SCHEMBL7087320 0.59
SCHEMBL6955696 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7109338-B2 For use in the prophylaxis and the treatment of Picornavirus and human rotavirus infections. MARUISHI PHARMACEUTICAL CO., LTD. (JP) 2006-09-19 US claimed
US-20040009977-A1 1,2-disubstituted 1,4-dihydro-4-oxoquinoline compounds MARUISHI PHARMACEUTICAL CO., LTD. (JP) 2004-01-15 US claimed
EP-1081138-A1 1,2-disubstituted 1,4-dihydro-4-oxoquinoline compounds Maruishi Pharmaceutical Co., Ltd. (JP) 2001-03-07 EP claimed
US-7319153-B2 6,13-Bis(thienyl)pentacene compounds 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-01-15 US disclosed
WO-2007016115-A2 6,13-BIS(THIENYL)PENTACENE COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-02-08 WO disclosed
US-20070023748-A1 6,13-Bis(thienyl)pentacene compounds 3M INNOVATIVE PROPERTIES COMPANY 2007-02-01 US disclosed
US-7109338-B2 For use in the prophylaxis and the treatment of Picornavirus and human rotavirus infections. MARUISHI PHARMACEUTICAL CO., LTD. (JP) 2006-09-19 US disclosed
US-20040009977-A1 1,2-disubstituted 1,4-dihydro-4-oxoquinoline compounds MARUISHI PHARMACEUTICAL CO., LTD. (JP) 2004-01-15 US disclosed
EP-1380575-A1 1,2-disubstituted 1,4-dihydro-4-oxoquinoline compounds Maruishi Pharmaceutical Co., Ltd. (JP) 2004-01-14 EP disclosed
US-6541470-B1 Have a potent antiviral activity against picornaviruses and rotaviruses. MARUISHI PHARMACEUTICAL CO., LTD. (JP) 2003-04-01 US disclosed
EP-1081138-A1 1,2-disubstituted 1,4-dihydro-4-oxoquinoline compounds Maruishi Pharmaceutical Co., Ltd. (JP) 2001-03-07 EP disclosed
WO-1989009212-A1 NEW 2,3,4-SUBSTITUTED IMIDAZOLS AND 3,4,5-SUBSTITUTED 1,2,4-TRIAZOLS, PREPARATION AND USE THEREOF BOEHRINGER INGELHEIM KG (DE) 1989-10-05 WO disclosed
EP-0335381-A1 2,3,4-Substituted imidazoles and 3,4,5-substituted 1,2,4-triazoles, their preparation and their use BOEHRINGER INGELHEIM KG (DE) 1989-10-04 EP disclosed