SCHEMBL4891075

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1136988	0.90	MET (0.57)	METKDRNPC1MAPTMAPK1
	SCHEMBL4730654	0.80	MET (0.70)	METKDRJAK2JAK3
	SCHEMBL14836435	0.78	IKBKB (0.48)	METKDRPLK4AURKAIKBKB
	SCHEMBL16617012	0.77	AURKA (0.49)	METKDRPLK4AURKAIKBKB
	SCHEMBL4733743	0.77	RAF1 (0.54)	METKDRNPC1RAB9A
	SCHEMBL4731957	0.77	GCK (0.46)	METKDRGSK3A
	SCHEMBL4730251	0.76	MET (0.44)	METMAP4K4
	SCHEMBL2763172	0.75	MET (0.44)	METKDRGSK3A
	SCHEMBL24741603	0.73	MEN1 (0.54)	MAP4K4SYKNPC1RAB9A
	SCHEMBL30108336	0.73	MEN1 (0.54)	MAP4K4SYKNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.