⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483028 | 0.84 | KDM4E (0.30) | — | |
| SCHEMBL130062 | 0.84 | KMT2A (0.34) | — | |
| SCHEMBL2457205 | 0.81 | LMNA (0.34) | — | |
| SCHEMBL5550945 | 0.79 | KDM4E (0.38) | — | |
| SCHEMBL11401037 | 0.79 | — | — | |
| SCHEMBL8021690 | 0.78 | — | — | |
| SCHEMBL2457313 | 0.78 | LMNA (0.38) | — | |
| SCHEMBL2458784 | 0.76 | — | — | |
| SCHEMBL5358574 | 0.76 | SLC6A2 (0.30) | — | |
| SCHEMBL3043431 | 0.76 | LMNA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312271-A1 | AZABENZIMIDAZOLYL COMPOUNDS | PFIZER INC. | 2008-12-18 | — | — | US | claimed |