Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.45 |
| ▸ | S100B | P04271 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13368811 | 1.00 | RAB9A (0.52) | RAB9AKMT2ANPC1GRIN2DGRIN3B | |
| SCHEMBL3585101 | 1.00 | RAB9A (0.52) | RAB9AKMT2ANPC1GRIN2DGRIN3B | |
| SCHEMBL3585094 | 1.00 | RAB9A (0.52) | RAB9AKMT2ANPC1GRIN2DGRIN3B | |
| SCHEMBL4891605 | 1.00 | RAB9A (0.52) | RAB9AKMT2ANPC1GRIN2DGRIN3B | |
| SCHEMBL3585089 | 1.00 | RAB9A (0.52) | RAB9AKMT2ANPC1GRIN2DGRIN3B | |
| SCHEMBL1129966 | 0.86 | KMT2A (0.59) | RAB9AKMT2ANPC1GRIN2DGRIN3B | |
| SCHEMBL1129964 | 0.86 | KMT2A (0.59) | RAB9AKMT2ANPC1GRIN2DGRIN3B | |
| SCHEMBL19233521 | 0.84 | KMT2A (0.62) | RAB9AKMT2ANPC1GRIN2DGRIN3B | |
| SCHEMBL31351734 | 0.81 | KMT2A (0.49) | RAB9AKMT2AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL31351777 | 0.81 | KMT2A (0.49) | RAB9AKMT2AGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853352-B2 | Functionalized polymer and method for making | BRIDGESTONE CORPORATION (JP) | 2014-10-07 | — | — | US | disclosed |
| US-20080154020-A1 | introducing imine compounds into carbanionic (living) polymers, that can interact with particle filler such as carbon black and silica | BRIDGESTONE CORPORATION (JP) | 2008-06-26 | — | — | US | disclosed |