SCHEMBL4891744

SCHEMBL4891744

CCO[Si](CCc1nccn1C(C)C)(OCC)OCC

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 1/20 0.34
ADORA3 P0DMS8 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA2B P29275 1/20 0.33
ADORA1 P30542 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4890507 0.91 FPR2 (0.33) FPR2ADORA3ADORA2AADORA2BADORA1
SCHEMBL4898433 0.84 MC4R (0.35) FPR2ADORA3ADORA2AADORA2BADORA1
SCHEMBL4898302 0.81 ADA (0.32)
SCHEMBL4896303 0.81 ADA (0.32)
SCHEMBL14254645 0.78 KCNH2 (0.35) FPR2ADORA3ADORA2AADORA2BADORA1
SCHEMBL4895866 0.78 CYP1A2 (0.35) ADORA3ADORA2AADORA2BADORA1
SCHEMBL4892715 0.75 MC4R (0.34) ADORA3ADORA2AADORA2BADORA1
SCHEMBL4892834 0.74 ADA (0.32)
SCHEMBL4898585 0.74 ADA (0.32)
SCHEMBL4077931 0.74 MAPT (0.35) FPR2ADORA3ADORA2AADORA2BADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080274305-A1 Liquid Crystal Sealant and Liquid Crystal Display Cell Utilizing the Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-11-06 US disclosed
EP-1780587-A1 LIQUID CRYSTAL SEALANT AND LIQUID CRYSTAL DISPLAY CELL UTILIZING THE SAME Nippon Kayaku Kabushiki Kaisha (JP) 2007-05-02 EP disclosed