SCHEMBL4891835

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5107131	0.86	MEN1 (0.73)	ABCG2PDE5AMEN1KMT2AMAPT
	SCHEMBL2304172	0.82	KDM1A (0.65)	ABCG2MEN1KMT2AMAPTLMNA
	SCHEMBL4089757	0.82	CYP1A2 (0.67)	PDE5AMEN1KMT2AMAPTLMNA
	SCHEMBL1063734	0.82	MEN1 (0.76)	ABCG2PDE5AMEN1KMT2AMAPT
	SCHEMBL4085200	0.82	PDE5A (1.00)	ABCG2PDE5AMEN1KMT2AMAPT
	SCHEMBL9776700	0.81	SLC2A1 (0.83)	MAPTLMNAKDM4EALDH1A1SMN1; SMN2
	SCHEMBL1056599	0.81	ABCG2 (1.00)	ABCG2PDE5AMEN1KMT2AMAPT
	SCHEMBL31375190	0.81	LATS1 (1.00)	LMNAKDM4ELATS1POLB
	SCHEMBL27400911	0.81	LATS1 (0.50)	ABCG2PDE5AMEN1KMT2AMAPT
	SCHEMBL26177128	0.81	LATS1 (1.00)	LMNAKDM4ELATS1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.