Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 18/20 | 0.56 |
| ▸ | CHUK | O15111 | 18/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CIT | O14578 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3416170 | 0.88 | IKBKB (0.65) | IKBKBCHUK | |
| Trifluoroacetic Acid SCHEMBL3417472 | 0.86 | IKBKB (0.57) | IKBKBCHUKCYP2C9CIT | |
| Trifluoroacetic Acid SCHEMBL3416482 | 0.86 | IKBKB (0.59) | IKBKBCHUKCYP2C9CIT | |
| Trifluoroacetic Acid SCHEMBL3415398 | 0.85 | IKBKB (0.58) | IKBKBCHUKCYP2C9CIT | |
| SCHEMBL4892649 | 0.85 | IKBKB (0.48) | IKBKBCHUKCYP2C9CIT | |
| SCHEMBL3413862 | 0.85 | IKBKB (0.64) | IKBKBCHUKCYP2C9CIT | |
| SCHEMBL3412082 | 0.84 | IKBKB (0.67) | IKBKBCHUKCYP2C9CIT | |
| SCHEMBL3411075 | 0.83 | IKBKB (0.66) | IKBKBCHUKCYP2C9CIT | |
| Trifluoroacetic Acid SCHEMBL3617324 | 0.83 | IKBKB (0.59) | IKBKBCHUKCYP2C9CIT | |
| SCHEMBL3417524 | 0.82 | IKBKB (0.65) | IKBKBCHUKCYP2C9CIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176891-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-07-24 | — | — | US | disclosed |
| US-20080146606-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176891-A1 | NOVEL COMPOUNDS | NFKBIA, IKBKG, IKBKE | IKBKB 4/4885CHUK 8/4885CYP2C9 3454/4885 |
| US-20080146606-A1 | NOVEL COMPOUNDS | NFKBIA, IKBKG, IKBKE | IKBKB 4/4885CHUK 8/4885CYP2C9 3454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.