SCHEMBL489207

SCHEMBL489207

S=C1NC=CCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11187202 0.76
SCHEMBL20719507 0.71
SCHEMBL27378961 0.67
SCHEMBL11318485 0.65
SCHEMBL6785405 0.62 NOS2 (0.32)
SCHEMBL15388886 0.59
SCHEMBL602037 0.56
SCHEMBL17125674 0.53
SCHEMBL586833 0.52
SCHEMBL3901807 0.50

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462519-A Dihydropyrimidine thioketone compound and application thereof in resisting porcine epidemic diarrhea virus 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) 2025-02-18 CN claimed
US-20250051314-A1 SMALL MOLECULE INHIBITORS OF INTERFERON GAMMA SIGNALING PARIS SCIENCES ET LETTRES (FR) 2025-02-13 US claimed
CN-117551260-A Polymer containing 3, 4-dihydropyrimidine-2-thione structure in main chain and preparation method thereof 清华大学 2024-02-13 CN claimed
CN-110437100-B Preparation method and application of novel ionic salicylaldehyde Schiff base zirconium complex 山西医科大学 2022-03-11 CN claimed
CN-108586361-B Isolongifolane dihydro-pyrimidine thioketone compound and preparation method and application thereof 南京林业大学 2021-03-12 CN claimed
CN-108822136-B Isolongifolane thiazolopyrimidine compound, and preparation method and application thereof 南京林业大学 2019-12-27 CN claimed
US-10463901-B2 Use of metal-accumulating plants for the preparation of catalysts that can be used in chemical reactions CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2019-11-05 US claimed
US-20180015317-A1 USE OF METAL-ACCUMULATING PLANTS FOR THE PREPARATION OF CATALYSTS THAT CAN BE USED IN CHEMICAL REACTIONS UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES (FR) 2018-01-18 US claimed
US-9744391-B2 Use of metal-accumulating plants for implementing chemical reactions CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2017-08-29 US claimed
US-20150376224-A1 USE OF COMPOSITIONS OBTAINED BY CALCINING PARTICULAR METAL-ACCUMULATING PLANTS FOR IMPLEMENTING CATALYTICAL REACTIONS UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES (FR) 2015-12-31 US claimed
EP-2504096-A1 USE OF METAL-ACCUMULATING PLANTS FOR THE PREPARATION OF CATALYSTS THAT CAN BE USED IN CHEMICAL REACTIONS Centre National de la Recherche Scientifique (FR) 2012-10-03 EP claimed
WO-2011064487-A1 USE OF METAL-ACCUMULATING PLANTS FOR THE PREPARATION OF CATALYSTS THAT CAN BE USED IN CHEMICAL REACTIONS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2011-06-03 WO claimed
US-20090104116-A1 COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF JERINI AG (DE) 2009-04-23 US claimed
EP-1979342-A1 COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF Jerini AG (DE) 2008-10-15 EP claimed
WO-2007088041-A1 COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF JERINI AG (DE) 2007-08-09 WO claimed
WO-2002066443-A2 2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE DERIVATIVES ONO PHARMACEUTICAL CO., LTD. (JP) 2002-08-29 WO claimed
US-5342937-A Extraction of metals especially gallium ZENECA, LIMITED (GB) 1994-08-30 US claimed
US-5206115-A High sensitivity, rapid image completion, pitch-black color tone FUJI PHOTO FILM CO., LTD. (JP) 1993-04-27 US claimed
EP-0409223-A2 3,4-Di-(hydro)-2H,6H-pyrimido[2,1-b][1,3]thiazine derivatives and 1,2,3,4-tetra-(hydro)-pyrimidin-2-thiones, process for their preparation and medicament containing them EGIS GYOGYSZERGYAR (HU) 1991-01-23 EP claimed
EP-0408203-A2 Heterocyclic thione ZENECA LIMITED (GB) 1991-01-16 EP claimed