SCHEMBL489227

SCHEMBL489227

C=CC(O)[N]C(O)C=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10881384 0.72
SCHEMBL9067092 0.72
SCHEMBL10523440 0.72
SCHEMBL347195 0.70
SCHEMBL15402072 0.65
SCHEMBL30980 0.65
Bromide SCHEMBL6129608 0.64
Bromide SCHEMBL6129607 0.64
SCHEMBL3416266 0.61
SCHEMBL2893448 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 734 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023215238-A1 PREPARATION AND USES OF 7-AZAINDENOISOQUINOLINES PURDUE RESEARCH FOUNDATION (US) 2023-11-09 WO claimed
US-20220000737-A1 COMPOSITION COMPRISING AT LEAST TWO ANIONIC SURFACTANTS, A NONIONIC SURFACTANT, AN AMPHOTERIC SURFACTANT, AND AT LEAST ONE DIRECT DYE L'OREAL (FR) 2022-01-06 US claimed
WO-2021001393-A1 COSMETIC COMPOSITION COMPRISING SILICONES BEARING A CARBOXYLIC GROUP AND ANIONIC DIRECT DYES, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2021-01-07 WO claimed
US-10716744-B2 Multi-step hair dyeing process using at least one titanium salt and a synthetic direct dye L'OREAL (FR) 2020-07-21 US claimed
EP-3638199-A1 PROCESS FOR DYEING KERATIN FIBRES USING AT LEAST ONE DIRECT DYE AND AT LEAST ONE DISULFIDE, THIOL OR PROTECTED-THIOL FLUORESCENT DYE L'Oreal (FR) 2020-04-22 EP claimed
US-20200100999-A1 PROCESS FOR DYEING KERATIN FIBRES USING AT LEAST ONE DIRECT DYE AND AT LEAST ONE DISULFIDE, THIOL OR PROTECTED-THIOL FLUORESCENT DYE L'OREAL (FR) 2020-04-02 US claimed
US-20200095243-A1 AZAINDENOISOQUINOLINE COMPOUNDS AND USES THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2020-03-26 US claimed
EP-3558993-A1 AZAINDENOISOQUINOLINE COMPOUNDS AND USES THEREOF Purdue Research Foundation (US) 2019-10-30 EP claimed
EP-3554463-A1 COMPOSITION COMPRISING AT LEAST TWO ANIONIC SURFACTANTS, A NONIONIC SURFACTANT, AN AMPHOTERIC SURFACTANT, AND AT LEAST ONE DIRECT DYE L'Oréal (FR) 2019-10-23 EP claimed
US-10292920-B2 Composition for dyeing keratin fibers L'OREAL (FR) 2019-05-21 US claimed
EP-0223124-A1 Substituted aminosulfonyl 6-nitrobenzoic-esters or amides, processes for their preparation and pharmaceutical compositions containing them MERCK & CO. INC. (US) 1987-05-27 EP claimed
US-4647588-A 2-(substituted sulfamyl)-6-nitrobenzoic acid amides and pharmaceutical compositions MERCK & CO., INC. (US) 1987-03-03 US claimed
EP-0207901-A1 Antianaphylactic and antibronchospastic N-benzhydryldiazacycloalkylalkananilides RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) 1987-01-07 EP claimed
EP-0197386-A1 2-(Substituted sulfamyl) derivatives of 6-nitrobenzoic acid, process for their preparation and pharmaceutical compositions containing them MERCK & CO. INC. (US) 1986-10-15 EP claimed
US-4562211-A ANTIDEPRESSANTS MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1985-12-31 US claimed
EP-0094349-A2 Use of quinoline derivatives for the protection of cultivated plants CIBA-GEIGY AG (CH) 1983-11-16 EP claimed
US-4308014-A AN UNSATURATED ESTER OR AMIDE, A TITANIUM ALKOXIDE OR A TRIALKOXY SILANE, A FREE RADICAL CATALYST AND AN ACTIVATOR; DENTISTRY KANEBO LTD. (JP) 1981-12-29 US claimed
EP-0017937-A2 Bonding compositions to the hard tissue of human body KANEBO, LTD. (JP) 1980-10-29 EP claimed
US-4016263-A BACTERICIDES BOEHRINGER INGELHEIM GMBH (DT) 1977-04-05 US claimed
US-3931204-A CARDIOVASCULAR U.C.B. SOCIETE ANONYME (BE) 1976-01-06 US claimed