Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.65 |
| ▸ | PPARA | Q07869 | 8/20 | 0.65 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4892484 | 1.00 | PPARG (0.65) | PPARGPPARAAURKAMEN1MAPT | |
| SCHEMBL4885784 | 0.87 | PPARG (0.67) | PPARGPPARA | |
| SCHEMBL4892014 | 0.82 | PPARG (0.65) | PPARGPPARA | |
| SCHEMBL5729481 | 0.81 | PPARG (0.60) | PPARGPPARA | |
| SCHEMBL4895336 | 0.79 | PPARG (0.68) | PPARGPPARA | |
| SCHEMBL14111177 | 0.79 | PPARG (0.81) | PPARGPPARA | |
| SCHEMBL4893539 | 0.79 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL4896308 | 0.79 | PPARG (0.67) | PPARGPPARAMEN1KMT2A | |
| SCHEMBL14111144 | 0.79 | PPARG (0.73) | PPARGPPARA | |
| SCHEMBL4889054 | 0.79 | PPARG (0.87) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080167310-A1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | GOSSETT LYNN STACY | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167310-A1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | PPARG, PPARA, PPARD | PPARG 1/4885PPARA 2/4885AURKA 4425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.