Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.60 |
| ▸ | PPARA | Q07869 | 13/20 | 0.60 |
| ▸ | PPARD | Q03181 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4885784 | 0.83 | PPARG (0.67) | PPARGPPARA | |
| SCHEMBL4892484 | 0.81 | PPARG (0.65) | PPARGPPARA | |
| SCHEMBL4892489 | 0.81 | PPARG (0.65) | PPARGPPARA | |
| SCHEMBL4895336 | 0.80 | PPARG (0.68) | PPARGPPARAPPARD | |
| SCHEMBL4896308 | 0.80 | PPARG (0.67) | PPARGPPARAPPARDLRRK2 | |
| SCHEMBL14111159 | 0.79 | PPARG (0.66) | PPARGPPARAPPARD | |
| SCHEMBL4892014 | 0.78 | PPARG (0.65) | PPARGPPARAPPARD | |
| SCHEMBL14111353 | 0.77 | PPARG (0.76) | PPARGPPARAPPARD | |
| SCHEMBL14111144 | 0.77 | PPARG (0.73) | PPARGPPARAPPARDGAA | |
| SCHEMBL4889117 | 0.76 | PPARG (0.66) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401434-B1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | LILLY CO ELI (US) | 2006-11-15 | — | — | EP | disclosed |