Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 17/20 | 0.63 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3338345 | 0.78 | HTR6 (1.00) | HTR6HTR1AHTR7DRD2HTR2A | |
| SCHEMBL7864888 | 0.74 | HTR6 (0.58) | HTR6HTR7HTR2CHTR2A | |
| SCHEMBL9147029 | 0.69 | HTR6 (0.56) | HTR6 | |
| SCHEMBL3337191 | 0.65 | HTR6 (0.86) | HTR6HTR1AHTR7 | |
| SCHEMBL7867260 | 0.64 | HTR2C (0.53) | HTR6HTR7HTR2CDRD2HTR2A | |
| SCHEMBL24670969 | 0.64 | HTR2C (0.51) | HTR6HTR1AHTR7HTR2CDRD2 | |
| SCHEMBL3327847 | 0.64 | HTR6 (1.00) | HTR6HTR1AHTR7HTR2CDRD2 | |
| SCHEMBL27336067 | 0.64 | HTR6 (0.60) | HTR6HTR1AHTR7HTR2CDRD2 | |
| SCHEMBL3338167 | 0.63 | HTR6 (1.00) | HTR6HTR1AHTR7DRD2HTR2A | |
| SCHEMBL6599102 | 0.63 | HTR2C (0.65) | HTR6HTR7HTR2CDRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984351-A1 | COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | Memory Pharmaceuticals Corporation (US) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007098418-A1 | COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2007-08-30 | — | — | WO | disclosed |