Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.63 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.60 |
| ▸ | DRD4 | P21917 | 3/20 | 0.56 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.56 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.55 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.55 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.55 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.55 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.55 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.55 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.55 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.55 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4881110 | 0.93 | MAPKAPK2 (0.62) | MAPKAPK2MCHR1DRD4SLC6A12SLC6A13 | |
| SCHEMBL4886522 | 0.90 | MAPKAPK2 (0.61) | MAPKAPK2MCHR1DRD4SLC6A12SLC6A13 | |
| SCHEMBL4894204 | 0.89 | MAPKAPK2 (0.62) | MAPKAPK2MCHR1DRD4SLC6A12SLC6A13 | |
| SCHEMBL4892360 | 0.89 | MAPKAPK2 (0.64) | MAPKAPK2MCHR1DRD4SLC6A12SLC6A13 | |
| Hydrochloric Acid SCHEMBL4887420 | 0.88 | MAPKAPK2 (0.56) | MAPKAPK2MCHR1DRD4 | |
| SCHEMBL4885734 | 0.85 | MAPKAPK2 (0.62) | MAPKAPK2MCHR1DRD4SLC6A12SLC6A13 | |
| SCHEMBL4891195 | 0.85 | DRD4 (0.57) | MAPKAPK2MCHR1DRD4SLC6A12SLC6A13 | |
| SCHEMBL4889803 | 0.85 | PRKAA2 (0.59) | MAPKAPK2MCHR1DRD4SLC6A12SLC6A13 | |
| SCHEMBL4889804 | 0.84 | MAPKAPK2 (0.60) | MAPKAPK2DRD4SLC6A12SLC6A13SIGMAR1 | |
| SCHEMBL4882258 | 0.84 | MAPKAPK2 (0.59) | MAPKAPK2DRD4SLC6A12SLC6A13SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080039499-A1 | Chemical Compounds | BOWER JUSTIN F | 2008-02-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039499-A1 | Chemical Compounds | CCR1, CCL11, CXCR1 | MAPKAPK2 2482/4885MCHR1 157/4885DRD4 513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.