Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | FOLH1 | Q04609 | 8/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.57 |
| ▸ | SYK | P43405 | 1/20 | 0.56 |
| ▸ | KLK7 | P49862 | 2/20 | 0.56 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4883784 | 0.97 | MAPT (0.61) | MAPTFOLH1HTTITGB3ITGA2B | |
| SCHEMBL1022850 | 0.91 | MAPT (0.66) | MAPTFOLH1HTTITGB3ITGA2B | |
| SCHEMBL30915257 | 0.89 | MAPT (0.67) | MAPTFOLH1HTTITGB3ITGA2B | |
| SCHEMBL8838459 | 0.89 | MAPT (0.67) | MAPTFOLH1HTTITGB3ITGA2B | |
| SCHEMBL29401232 | 0.89 | MAPT (0.67) | MAPTFOLH1HTTITGB3ITGA2B | |
| SCHEMBL31429918 | 0.88 | MAPT (0.66) | MAPTFOLH1HTTITGB3ITGA2B | |
| Bicarbonate SCHEMBL5175781 | 0.88 | MAPT (0.66) | MAPTFOLH1HTTITGB3ITGA2B | |
| SCHEMBL1134604 | 0.88 | MAPT (0.66) | MAPTFOLH1HTTITGB3ITGA2B | |
| SCHEMBL19057198 | 0.88 | MAPT (0.54) | MAPTFOLH1HTTITGB3ITGA2B | |
| SCHEMBL16279057 | 0.87 | MAPT (0.62) | MAPTFOLH1HTTITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275018-A1 | ANTIBACTERIAL AMIDE-MACROCYCLES V | AICURIS GMBH & CO. KG (DE) | 2008-11-06 | — | — | US | disclosed |
| EP-1869068-A1 | ANTIBACTERIAL AMIDE-MACROCYCLES V | AiCuris GmbH & Co. KG (DE) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006103015-A1 | ANTIBACTERIAL AMIDE-MACROCYCLES V | AICURIS GMBH & CO. KG (DE) | 2006-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275018-A1 | ANTIBACTERIAL AMIDE-MACROCYCLES V | ARG1, HRH3, H1-0 | MAPT 4840/4885FOLH1 3653/4885HTT 1449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.