SCHEMBL4893737

SCHEMBL4893737

CCCCCCCCSCCCl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
ALDH1A1 P00352 1/20 0.52
CES2 O00748 3/20 0.46
THRB P10828 2/20 0.46
GMNN O75496 1/20 0.46
TP53 P04637 1/20 0.46
POLB P06746 1/20 0.46
MAPT P10636 1/20 0.46
CYP2C9 P11712 1/20 0.46
BLM P54132 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CA2 P00918 1/20 0.45
TDP1 Q9NUW8 1/20 0.43
FAAH O00519 4/20 0.41
CES1 P23141 4/20 0.41
PLA2G6 O60733 1/20 0.41
PRKD3 O94806 2/20 0.37
PRKCG P05129 2/20 0.37
PRKCB P05771 2/20 0.37
PRKCA P17252 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8407592 1.00 TSHR (0.52) TSHRALDH1A1CES2THRBGMNN
SCHEMBL8967573 1.00 TSHR (0.52) TSHRALDH1A1CES2THRBGMNN
SCHEMBL8404269 0.97 TSHR (0.50) TSHRALDH1A1CES2THRBGMNN
SCHEMBL539318 0.97
SCHEMBL10987810 0.92 TSHR (0.63) TSHRALDH1A1CES2THRBGMNN
SCHEMBL3431156 0.92 TSHR (0.63) TSHRALDH1A1CES2THRBGMNN
SCHEMBL8407803 0.92 TSHR (0.63) TSHRALDH1A1CES2THRBGMNN
SCHEMBL539270 0.89
SCHEMBL22023003 0.87 FAAH (0.47) TSHRALDH1A1GMNNTP53POLB
SCHEMBL22023001 0.87 FAAH (0.47) TSHRALDH1A1GMNNTP53POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080161215-A1 Additive For Lubricant IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 US disclosed
EP-1783196-A1 ADDITIVE FOR LUBRICANT IDEMITSU KOSAN CO., LTD. (JP) 2007-05-09 EP disclosed
EP-0574331-B1 Tone control of photographic images EASTMAN KODAK CO (US) 1999-07-28 EP disclosed
EP-0573373-B1 Tone control of photographic silver images EASTMAN KODAK CO (US) 1999-07-14 EP disclosed
EP-0575262-B1 Radiographic elements with improved covering power EASTMAN KODAK CO (US) 1999-07-07 EP disclosed
US-5314790-A Tetrazoles or triazoles EASTMAN KODAK COMPANY (US) 1994-05-24 US disclosed
US-5292627-A Azole to modify tone EASTMAN KODAK COMPANY (US) 1994-03-08 US disclosed
US-5292631-A Radiographic elements with improved covering power EASTMAN KODAK COMPANY (US) 1994-03-08 US disclosed
EP-0575262-A2 Radiographic elements with improved covering power EASTMAN KODAK COMPANY (US) 1993-12-22 EP disclosed
EP-0574331-A2 Tone control of photographic images EASTMAN KODAK COMPANY (US) 1993-12-15 EP disclosed
EP-0573373-A2 Tone control of photographic silver images EASTMAN KODAK COMPANY (US) 1993-12-08 EP disclosed