Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2285290 | 0.86 | CYP1A2 (0.31) | — | |
| SCHEMBL4886251 | 0.61 | CYP1A2 (0.31) | — | |
| SCHEMBL6422784 | 0.60 | AURKA (0.35) | — | |
| SCHEMBL9275405 | 0.59 | PARP1 (0.44) | PARP1 | |
| SCHEMBL30082247 | 0.59 | PARP1 (0.44) | PARP1 | |
| SCHEMBL17766590 | 0.58 | PARP1 (0.47) | PARP1 | |
| SCHEMBL29437799 | 0.57 | ALDH1A1 (0.42) | PARP1 | |
| SCHEMBL44930 | 0.57 | ALDH1A1 (0.42) | PARP1 | |
| SCHEMBL23890397 | 0.55 | PARP1 (0.39) | PARP1 | |
| SCHEMBL7335586 | 0.54 | PARP1 (0.42) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221090-A1 | HCV NS5B Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221090-A1 | HCV NS5B Inhibitors | EIF2AK2, HAVCR2, EIF5B | PARP1 3298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.