Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.36 |
| ▸ | GAK | O14976 | 5/20 | 0.36 |
| ▸ | IL2 | P60568 | 1/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4900781 | 0.73 | CYP1A1 (0.50) | CYP1A1CYP1A2CYP1B1MTORJAK2 | |
| SCHEMBL4898931 | 0.72 | FYN (0.50) | MTORFYNJAK2ECE1MAP4K1 | |
| SCHEMBL1868218 | 0.64 | MAPK10 (0.53) | CYP1A1CYP1A2CYP1B1JAK2JAK3 | |
| SCHEMBL15545775 | 0.64 | CYP1A2 (0.57) | CYP1A1CYP1A2CYP1B1NPC1MAPT | |
| SCHEMBL4891073 | 0.64 | CTSC (0.40) | CYP1A1CYP1A2CYP1B1NPC1RAB9A | |
| SCHEMBL4894058 | 0.63 | CTSC (0.40) | CYP1A1CYP1A2CYP1B1MAPK1 | |
| SCHEMBL4901213 | 0.63 | CTSC (0.47) | MAP4K1 | |
| SCHEMBL4902331 | 0.62 | SMPD3 (0.49) | CYP1A1CYP1A2CYP1B1MAPTRAB9A | |
| SCHEMBL28508400 | 0.62 | KDM4E (0.49) | NPC1MAPTRAB9ASMN1; SMN2TRPM8 | |
| SCHEMBL4901972 | 0.61 | CYP1A1 (0.55) | CYP1A1CYP1A2CYP1B1JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | ICAGEN, INC. (US) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | KCNJ2, KCNH2, KCNQ1 | CYP1A1 2689/4885CYP1A2 2682/4885CYP1B1 3572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.