Isophthalic Acid

Isophthalic Acid

SCHEMBL4894286

O=C(O)c1ccc(C(=O)O)c(C(=O)O)c1.O=C(O)c1cccc(C(=O)O)c1

nearest known ligand 0.71

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.71
HSD17B10 Q99714 3/20 0.62
CDC25A P30304 1/20 0.62
CDC25B P30305 1/20 0.62
POLB P06746 2/20 0.55
TDP1 Q9NUW8 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA6 P23280 1/20 0.54
CA9 Q16790 1/20 0.54
PTPN1 P18031 1/20 0.53
KMO O15229 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
HPGD P15428 1/20 0.50
MYC P01106 1/20 0.49
AKR1C3 P42330 2/20 0.49
AKR1B10 O60218 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL5165105 0.98 KDM4E (0.69) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL464994 0.94 KDM4E (0.70) KDM4EHSD17B10CDC25ACDC25BPOLB
Benzene SCHEMBL9407020 0.93 KDM4E (0.73) KDM4EHSD17B10CDC25ACDC25BPOLB
Pyromellitic Acid SCHEMBL9244438 0.92 KDM4E (0.68) KDM4EHSD17B10CDC25ACDC25BPOLB
Isophthalic Acid SCHEMBL7528600 0.92 KDM4E (0.62) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL1683152 0.91 KDM4E (0.64) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL8160655 0.91 KDM4E (0.64) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL23861 0.91 KDM4E (0.69) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL23279 0.91 KDM4E (0.69) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL30163040 0.91 KDM4E (0.69) KDM4EHSD17B10CDC25ACDC25BPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4275189-A VISCOSITY STABLE POWDER COATING CARGILL, INCORPORATED (US) 1981-06-23 US claimed
US-20080171799-A1 Synthesis of Polymer Foam Using Sonic Energy REDMOND LINDSAY 2008-07-17 US disclosed
US-6013723-A MOLDED ARTICLE MADE OF A THERMOPLASTIC RESIN HAVING A NARROW MOLECULAR WEIGHT DISTRIBUTION, WHICH WAS POLYMERIZED USING A SINGLE-SITE CATALYST, LUBRICANT, AND ANTIOXIDANT; SUPERIOR IN PHYSICAL STRENGTH AND BLOCKING RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 2000-01-11 US disclosed
US-5906813-A Injection molded article used with photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1999-05-25 US disclosed