⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26577796 | 1.00 | — | — | |
| SCHEMBL26577798 | 1.00 | — | — | |
| SCHEMBL1192477 | 0.84 | — | — | |
| SCHEMBL20745912 | 0.78 | — | — | |
| SCHEMBL22983837 | 0.75 | — | — | |
| SCHEMBL17545626 | 0.73 | — | — | |
| SCHEMBL459723 | 0.68 | — | — | |
| SCHEMBL14734196 | 0.67 | — | — | |
| SCHEMBL3237784 | 0.65 | — | — | |
| SCHEMBL15229433 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205701-A1 | MACROCYCLIC HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| US-9156788-B2 | TRPV3 modulators | ABBVIE INC. (US) | 2015-10-13 | — | — | US | disclosed |
| US-8772500-B2 | TRPV3 modulators | ABBVIE INC. (US) | 2014-07-08 | — | — | US | disclosed |
| US-8772499-B2 | TRPV3 modulators | ABBVIE INC. (US) | 2014-07-08 | — | — | US | disclosed |
| US-20140080803-A1 | NOVEL TRPV3 MODULATORS | ABBVIE INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-20130150409-A1 | NOVEL TRPV3 MODULATORS | ABBVIE INC. (US) | 2013-06-13 | — | — | US | disclosed |
| US-20130131036-A1 | NOVEL TRPV3 MODULATORS | ABBVIE INC. (US) | 2013-05-23 | — | — | US | disclosed |
| US-20080033154-A1 | Process for Producing 3-Aminomethyltetrahydrofuran Derivative | MITSUI CHEMICALS, INC. (JP) | 2008-02-07 | — | — | US | disclosed |
| EP-1780205-A1 | METHOD FOR PRODUCING 3-AMINOMETHYLTETRAHYDROFURAN DERIVATIVE | Mitsui Chemicals, Inc. (JP) | 2007-05-02 | — | — | EP | disclosed |