Aclonifen

Aclonifen

SCHEMBL4894870

Nc1c([N+](=O)[O-])ccc(Oc2ccccc2)c1Cl.Nc1c([N+](=O)[O-])ccc(Oc2ccccc2)c1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
TTR P02766 1/20 1.00
ALB P02768 1/20 1.00
THRB P10828 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
PDE7A Q13946 2/20 0.50
PIN1 Q13526 3/20 0.46
MAPT P10636 2/20 0.44
ALDH1A1 P00352 1/20 0.44
HPSE Q9Y251 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
HTR6 P50406 1/20 0.43
HPGD P15428 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
LMNA P02545 1/20 0.41
F10 P00742 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aclonifen SCHEMBL29470834 1.00 MEN1 (1.00) MEN1KMT2ATTRALBTHRB
Aclonifen SCHEMBL55487 1.00 MEN1 (1.00) MEN1KMT2ATTRALBTHRB
Aclonifen SCHEMBL9711313 0.92 MEN1 (0.85) MEN1KMT2ATTRALBTHRB
Aclonifen SCHEMBL2297957 0.90 MEN1 (0.81) MEN1KMT2ATTRALBTHRB
SCHEMBL11064915 0.86 MEN1 (0.75) MEN1KMT2ATTRALBTHRB
SCHEMBL30623820 0.86 MEN1 (0.75) MEN1KMT2ATTRALBTHRB
SCHEMBL21681375 0.86 MEN1 (0.75) MEN1KMT2ATTRALBTHRB
Aclonifen SCHEMBL7589599 0.84 TDP1 (0.70) MEN1KMT2ATTRALBTHRB
SCHEMBL10883530 0.83 TDP1 (0.71) MEN1KMT2ATTRALBTHRB
Aclonifen SCHEMBL27389461 0.83 MEN1 (0.69) MEN1KMT2ATTRALBTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3746505-B1 COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME DOW SILICONES CORP (US) 2024-06-26 EP disclosed
EP-3906245-B1 MULTIFUNCTIONAL ORGANOSILICON COMPOUND AND RELATED METHODS, COMPOUNDS, AND COMPOSITIONS DOW SILICONES CORP (US) 2024-05-29 EP disclosed
US-20240124709-A1 COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME DOW GLOBAL TECHNOLOGIES LLC 2024-04-18 US disclosed
EP-3645640-B1 SILICONE-POLYETHER COPOLYMER, METHOD OF PREPARING SAME, AND SEALANT COMPRISING SAME DOW SILICONES CORP (US) 2024-03-06 EP disclosed
US-11884821-B2 Composition, polymer composite article formed therewith, and method of preparing same DOW SILICONES CORPORATION (US) 2024-01-30 US disclosed
WO-2023215360-A1 SILICONE-POLYETHER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORPORATION (US) 2023-11-09 WO disclosed
US-11807775-B2 Silicone-organic copolymer, sealants comprising same, and related methods DOW SILICONES CORPORATION (US) 2023-11-07 US disclosed
US-11760841-B2 Silicone-polycarbonate copolymer, sealants comprising same, and related methods DOW SILICONES CORPORATION (US) 2023-09-19 US disclosed
CN-113272364-B Silicone-polyacrylate copolymers, sealants including silicone-polyacrylate copolymers, and related methods 美国陶氏有机硅公司 2023-03-24 CN disclosed
CN-113272363-B Silicone-organic copolymers, sealants including silicone-organic copolymers, and related methods 美国陶氏有机硅公司 2023-02-17 CN disclosed
WO-2012134784-A1 COMPOSITIONS CONTAINING PHOSPHONATE CATALYSTS AND METHODS FOR THE PREPARATION AND USE OF THE COMPOSITIONS DOW CORNING CORPORATION (US) 2012-10-04 WO disclosed
WO-2012134788-A1 COMPOSITIONS CONTAINING PHOSPHATE CATALYSTS AND METHODS FOR THE PREPARATION AND USE OF THE COMPOSITIONS DOW CORNING CORPORATION (US) 2012-10-04 WO disclosed
US-20080118734-A1 Coating Compositions DOW CORNING IRELAND LTD. (IE) 2008-05-22 US disclosed
EP-1744836-A2 PROCESS AND APPARATUS FOR PLASMA COATING, SUBSTRATES COATED BY THIS METHOD OR APPARATUS Dow Corning Ireland Limited (IE) 2007-01-24 EP disclosed
WO-2005110626-A2 PROCESS AND APPARATUS FOR PLASMA COATING, SUBSTRATES COATED BY THIS METOD OR APPARATUS DOW CORNING IRELAND LIMITED (IE) 2005-11-24 WO disclosed
EP-0574418-B1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1998-11-11 EP disclosed
US-5688745-A Arylsulfonylureas and their use as herbicides and growth regulators HOECHST AKTIENGESELLSCHAFT (DE) 1997-11-18 US disclosed
US-5463081-A Chemical intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed
EP-0574418-A1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS Hoechst Schering AgrEvo GmbH (DE) 1993-12-22 EP disclosed
WO-1992013845-A1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-20 WO disclosed