Aclonifen

Aclonifen

SCHEMBL7589599

Nc1c([N+](=O)[O-])ccc(Oc2ccccc2)c1Cl.O=C(O)c1nc(Cl)ccc1Cl

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.70
MEN1 O00255 3/20 0.70
KMT2A Q03164 3/20 0.70
TTR P02766 2/20 0.70
ALB P02768 1/20 0.70
THRB P10828 1/20 0.70
MERTK Q12866 1/20 0.42
HPSE Q9Y251 1/20 0.41
PDE7A Q13946 2/20 0.40
PPOX P50336 1/20 0.40
PIN1 Q13526 2/20 0.40
MAPT P10636 5/20 0.38
LMNA P02545 4/20 0.38
ALDH1A1 P00352 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
F10 P00742 1/20 0.36
PTPN22 Q9Y2R2 1/20 0.36
GSR P00390 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aclonifen SCHEMBL29470834 0.84 MEN1 (1.00) TDP1MEN1KMT2ATTRALB
Aclonifen SCHEMBL4894870 0.84 MEN1 (1.00) TDP1MEN1KMT2ATTRALB
Aclonifen SCHEMBL55487 0.84 MEN1 (1.00) TDP1MEN1KMT2ATTRALB
Aclonifen SCHEMBL2297957 0.78 MEN1 (0.81) TDP1MEN1KMT2ATTRALB
Aclonifen SCHEMBL9711313 0.77 MEN1 (0.85) TDP1MEN1KMT2ATTRALB
Pyrithiobac SCHEMBL7579433 0.75 MEN1 (0.54) TDP1MEN1KMT2ATTRALB
SCHEMBL27300894 0.74 TDP1 (0.67) TDP1MEN1KMT2ATTRALB
Bispyribac SCHEMBL7575232 0.74 MEN1 (0.59) TDP1MEN1KMT2ATTRALB
Acifluorfen SCHEMBL9738897 0.74 TDP1 (0.79) TDP1MEN1KMT2ATTRALB
Acifluorfen SCHEMBL7577847 0.74 TDP1 (0.79) TDP1MEN1KMT2ATTRALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MEN1 4274/4885KMT2A 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.