Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 6/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCND3 | P30281 | 1/20 | 0.34 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4892348 | 0.93 | HCRTR1 (0.36) | HCRTR1HCRTR2DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL4901103 | 0.86 | CCND3 (0.37) | HCRTR1HCRTR2CDK4CCND1CCND3 | |
| SCHEMBL4896616 | 0.85 | HCRTR1 (0.41) | HCRTR1HCRTR2P2RX7KDM6BALDH1A1 | |
| SCHEMBL4899702 | 0.84 | HCRTR1 (0.40) | HCRTR1HCRTR2KDM6BCDK4CCND3 | |
| Hydrochloric Acid SCHEMBL5257872 | 0.83 | HCRTR1 (0.40) | HCRTR1HCRTR2KDM6BCDK4CCND3 | |
| SCHEMBL4904908 | 0.82 | PTK2 (0.38) | HCRTR1HCRTR2KDM6BALDH1A1CDK4 | |
| Hydrochloric Acid SCHEMBL4895695 | 0.81 | CDK4 (0.36) | HCRTR1HCRTR2CDK4CCND1CCND3 | |
| Hydrochloric Acid SCHEMBL4902615 | 0.79 | MAP4K1 (0.38) | HCRTR1HCRTR2KDM6BCDK4CCND1 | |
| SCHEMBL4891073 | 0.76 | CTSC (0.40) | CDK4CCND1CCND3CDK6NPC1 | |
| SCHEMBL4894058 | 0.75 | CTSC (0.40) | CDK4CCND1CCND3CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | ICAGEN, INC. (US) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | KCNJ2, KCNH2, KCNQ1 | HCRTR1 2726/4885HCRTR2 1689/4885DRD2 2025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.