SCHEMBL4895243

SCHEMBL4895243

[S]c1scc2ccccc12

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
CYP2A6 P11509 5/20 0.39
HSD17B10 Q99714 4/20 0.39
TSHR P16473 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
HPRT1 P00492 1/20 0.36
CYP1A2 P05177 5/20 0.33
HPGD P15428 2/20 0.33
ALOX12 P18054 1/20 0.33
HIF1A Q16665 1/20 0.33
CYP1B1 Q16678 1/20 0.33
THRB P10828 1/20 0.33
CYP3A4 P08684 1/20 0.32
KEAP1 Q14145 1/20 0.32
CNR2 P34972 1/20 0.32
CCR4 P51679 1/20 0.31
GPR3 P46089 1/20 0.31
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13261664 0.74 ALDH1A1 (0.43) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL1097973 0.72 CYP2A6 (0.41) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL2008188 0.72 CYP2A6 (0.41) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL276255 0.70 CYP1A2 (0.42) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL21177767 0.70 CYP2A6 (0.39) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL1536197 0.70 CYP2A6 (0.39) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL276253 0.70 ALDH1A1 (0.39) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL3149291 0.70 ALDH1A1 (0.42) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL1097974 0.70 CYP2A6 (0.48) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL2008190 0.70 ALDH1A1 (0.42) ALDH1A1CYP2A6HSD17B10TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080044149-A1 Polymerizable Composition TOYO INK MFG. CO., LTD. (JP) 2008-02-21 US disclosed
EP-1816152-A1 POLYMERIZABLE COMPOSITION TOYO INK MFG. CO., LTD. (JP) 2007-08-08 EP disclosed