Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 1.00 |
| ▸ | ALKBH3 | Q96Q83 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | ALPL | P05186 | 2/20 | 0.67 |
| ▸ | ALPI | P09923 | 1/20 | 0.67 |
| ▸ | ALPG | P10696 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | CASP1 | P29466 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15233806 | 0.80 | KDM4E (1.00) | KDM4EALKBH3KMT2ATDP1MAPT | |
| Hydrochloric Acid SCHEMBL15233848 | 0.79 | KDM4E (0.97) | KDM4EALKBH3KMT2ATDP1MAPT | |
| SCHEMBL20830313 | 0.79 | KDM4E (0.65) | KDM4EALKBH3KMT2ATDP1MAPT | |
| SCHEMBL20819217 | 0.76 | ALKBH3 (0.60) | KDM4EALKBH3KMT2ATDP1MAPT | |
| SCHEMBL20830336 | 0.76 | KDM4E (0.60) | KDM4EALKBH3KMT2ATDP1MAPT | |
| SCHEMBL20830332 | 0.75 | ALKBH3 (0.59) | KDM4EALKBH3KMT2ATDP1MAPT | |
| SCHEMBL20819220 | 0.74 | KDM4E (0.62) | KDM4EALKBH3KMT2ATDP1MAPT | |
| SCHEMBL20819222 | 0.74 | KDM4E (0.59) | KDM4EALKBH3KMT2ATDP1MAPT | |
| SCHEMBL20819988 | 0.73 | ALKBH3 (0.57) | KDM4EALKBH3KMT2ATDP1MAPT | |
| SCHEMBL20830329 | 0.72 | KDM4E (0.57) | KDM4EALKBH3KMT2ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080027044-A1 | Prodrug antibiotic screens | NORTHEASTERN UNIVERSITY | 2008-01-31 | — | — | US | disclosed |
| US-20080027044-A1 | Prodrug antibiotic screens | NORTHEASTERN UNIVERSITY | 2008-01-31 | — | — | US | disclosed |
| US-20080027044-A1 | Prodrug antibiotic screens | NORTHEASTERN UNIVERSITY | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027044-A1 | Prodrug antibiotic screens | O60361, PGLS, GUSB | KDM4E 2069/4885ALKBH3 1677/4885KMT2A 3307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.