SCHEMBL4895850

SCHEMBL4895850

NC(CCc1ccccc1)CCc1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.56
ANPEP P15144 3/20 0.55
ERAP1 Q9NZ08 2/20 0.55
ERAP2 Q6P179 1/20 0.55
TAAR1 Q96RJ0 3/20 0.52
CYP2A6 P11509 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
HTR2A P28223 1/20 0.52
LOXL2 Q9Y4K0 1/20 0.52
S1PR2 O95136 1/20 0.49
S1PR4 O95977 1/20 0.49
S1PR1 P21453 1/20 0.49
S1PR3 Q99500 1/20 0.49
CYP2D6 P10635 2/20 0.48
MAOA P21397 5/20 0.48
MAOB P27338 3/20 0.48
ALDH1A1 P00352 2/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
ALOX12 P18054 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3585497 0.91 HTR2A (0.56) EPHX1ANPEPERAP1ERAP2TAAR1
SCHEMBL19143919 0.89 TDP1 (0.54) EPHX1ANPEPERAP1ERAP2TAAR1
SCHEMBL18531940 0.89 EPHX1 (0.64) EPHX1ANPEPERAP1ERAP2TAAR1
SCHEMBL172466 0.89 S1PR1 (0.49) EPHX1ANPEPERAP1ERAP2TAAR1
SCHEMBL8599042 0.89 ANPEP (0.50) EPHX1ANPEPERAP1ERAP2TAAR1
SCHEMBL5323248 0.89 S1PR1 (0.49) EPHX1ANPEPERAP1ERAP2TAAR1
SCHEMBL3442080 0.88 HTR2A (0.52) EPHX1ANPEPERAP1ERAP2TAAR1
SCHEMBL11769571 0.88 EPHX1 (0.70) EPHX1ANPEPERAP1ERAP2TAAR1
SCHEMBL13452965 0.86 ANPEP (0.48) EPHX1ANPEPERAP1ERAP2TAAR1
SCHEMBL1148969 0.86 ANPEP (0.48) EPHX1ANPEPERAP1ERAP2TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4729588-A1 CATIONIC ELECTRODEPOSITED PAINT COMPOSITION AND METHOD FOR FORMING CURED ELECTRODEPOSITED COATING Nippon Paint Automotive Coatings Co., Ltd. (JP) 2026-04-22 EP disclosed
US-12480005-B2 Method for preparing cationic electrodeposition coating composition NIPPON PAINT AUTOMOTIVE COATINGS CO., LTD. (JP) 2025-11-25 US disclosed
US-20220332960-A1 CATIONIC ELECTRODEPOSITION COATING COMPOSITION NIPPON PAINT AUTOMOTIVE COATINGS CO., LTD. (JP) 2022-10-20 US disclosed
US-20220282098-A1 METHOD FOR PREPARING CATIONIC ELECTRODEPOSITION COATING COMPOSITION NIPPON PAINT AUTOMOTIVE COATINGS CO., LTD. (JP) 2022-09-08 US disclosed
EP-3354700-B1 METHOD FOR PREPARING CATIONIC ELECTRODEPOSITION COATING MATERIAL COMPOSITION NIPPON PAINT AUTOMOTIVE COATINGS CO LTD (JP) 2022-07-20 EP disclosed
EP-3998316-A1 CATIONIC ELECTRODEPOSITION COATING COMPOSITION Nippon Paint Automotive Coatings Co., Ltd. (JP) 2022-05-18 EP disclosed
EP-3978576-A1 METHOD FOR PREPARING CATIONIC ELECTRODEPOSITION COATING COMPOSITION Nippon Paint Automotive Coatings Co., Ltd. (JP) 2022-04-06 EP disclosed
WO-2021006220-A1 CATIONIC ELECTRODEPOSITION COATING COMPOSITION 日本ペイント・オートモーティブコーティングス株式会社 2021-01-14 WO disclosed
WO-2020241590-A1 METHOD FOR PREPARING CATIONIC ELECTRODEPOSITION COATING COMPOSITION 日本ペイント・オートモーティブコーティングス株式会社 2020-12-03 WO disclosed
EP-3354701-B1 METHOD FOR PREPARING CATIONIC ELECTRODEPOSITION COATING COMPOSITION NIPPON PAINT AUTOMOTIVE COATINGS CO LTD (JP) 2020-06-10 EP disclosed
US-5840736-A PEPTIDES FOR NERVE GROWTH VERTEX PHARMACEUTICALS INCORPORATED (US) 1998-11-24 US disclosed
WO-1998020891-A1 METHODS AND COMPOSITIONS FOR STIMULATING NEURITE GROWTH USING COMPOUNDS WITH AFFINITY FOR FKBP12 IN COMBINATION WITH NEUROTROPHIC FACTORS VERTEX PHARMACEUTICALS INCORPORATED (US) 1998-05-22 WO disclosed
EP-0839798-A2 Intermediates for preparating non-peptide retroviral protease inhibitors ABBOTT LABORATORIES (US) 1998-05-06 EP disclosed
EP-0797567-A1 NOVEL AMINO ACID DERIVATIVES WITH IMPROVED MULTI-DRUG RESISTANCE ACTIVITY Vertex Pharmaceuticals Incorporated (US) 1997-10-01 EP disclosed
US-5670675-A Retroviral protease inhibiting compounds ABBOTT LABORATORIES (US) 1997-09-23 US disclosed
US-5545750-A TREATING HUMAN IMMUNODEFICIENCY VIRUS ABBOTT LABORATORIES (US) 1996-08-13 US disclosed
US-5543423-A USED IN MULTI-DRUG RESISTANCE CANCER THERAPY VERTEX PHARMACEUTICALS, INCORPORATED (US) 1996-08-06 US disclosed
WO-1996015101-A1 NOVEL AMINO ACID DERIVATIVES WITH IMPROVED MULTI-DRUG RESISTANCE ACTIVITY VERTEX PHARMACEUTICALS INCORPORATED (US) 1996-05-23 WO disclosed
US-5142056-A Human immunodeficiency virus protease inhibitor ABBOTT LABORATORIES (US) 1992-08-25 US disclosed
EP-0402646-A1 Retroviral protease inhibiting compounds ABBOTT LABORATORIES (US) 1990-12-19 EP disclosed