SCHEMBL1148969

SCHEMBL1148969

CCC(N)CCc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 2/20 0.48
ERAP1 Q9NZ08 2/20 0.48
ERAP2 Q6P179 1/20 0.48
EPHX1 P07099 1/20 0.48
CTSC P53634 1/20 0.45
TAAR1 Q96RJ0 3/20 0.45
SLC6A2 P23975 2/20 0.45
CYP2A6 P11509 2/20 0.45
MAOA P21397 1/20 0.45
SLC6A4 P31645 1/20 0.45
SLC6A3 Q01959 1/20 0.45
SIGMAR1 Q99720 1/20 0.45
ADORA2A P29274 1/20 0.45
ADORA1 P30542 1/20 0.45
HTR2A P28223 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
LOXL2 Q9Y4K0 1/20 0.44
AOC3 Q16853 2/20 0.44
S1PR2 O95136 2/20 0.44
S1PR1 P21453 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13452965 1.00 ANPEP (0.48) ANPEPERAP1ERAP2EPHX1CTSC
SCHEMBL4323451 1.00 ANPEP (0.48) ANPEPERAP1ERAP2EPHX1CTSC
Hydrochloric Acid SCHEMBL7614131 0.98 ANPEP (0.47) ANPEPERAP1ERAP2EPHX1CTSC
SCHEMBL21058270 0.88 MMP12 (0.47) TAAR1S1PR2S1PR1S1PR3
SCHEMBL11098738 0.88 S1PR2 (0.49) EPHX1SLC6A2MAOASLC6A4SLC6A3
Hydrochloric Acid SCHEMBL7824072 0.87 MMP12 (0.46) TAAR1S1PR2S1PR1S1PR3
SCHEMBL4895850 0.86 EPHX1 (0.56) ANPEPERAP1ERAP2EPHX1TAAR1
SCHEMBL172466 0.85 S1PR1 (0.49) ANPEPERAP1ERAP2EPHX1TAAR1
SCHEMBL5323248 0.85 S1PR1 (0.49) ANPEPERAP1ERAP2EPHX1TAAR1
SCHEMBL3442080 0.80 HTR2A (0.52) ANPEPERAP1ERAP2EPHX1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113072923-B Nano capsule gel breaker with controllable delivery and release, and preparation method and application thereof 中国石油大学(华东) 2023-02-17 CN claimed
US-20220194969-A1 METAL HALIDE PEROVSKITE LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2022-06-23 US claimed
CN-113072923-A Nano-capsule gel breaker with controllable delivery and release, and preparation method and application thereof 中国石油大学(华东) 2021-07-06 CN claimed
WO-2020130592-A1 METAL HALIDE PEROVSKITE LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME 서울대학교산학협력단 2020-06-25 WO claimed
US-11833493-B2 Metal catalyst, method of C-N coupling using the same and applications of the same BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2023-12-05 US disclosed
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed
CN-113072923-B Nano capsule gel breaker with controllable delivery and release, and preparation method and application thereof 中国石油大学(华东) 2023-02-17 CN disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 US disclosed
US-20220297101-A1 METAL CATALYST, METHOD OF C-N COUPLING USING THE SAME AND APPLICATIONS OF THE SAME BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS 2022-09-22 US disclosed
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
US-11376576-B2 Metal catalyst, method of C—N coupling using the same and applications of the same BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2022-07-05 US disclosed
US-20220194969-A1 METAL HALIDE PEROVSKITE LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2022-06-23 US disclosed
EP-0934284-A1 SUBSTITUTED 2-AMINO-4-ALKYLAMINO-1,3,5-TRIAZINES AS HERBICIDES BAYER AG (DE) 1999-08-11 EP disclosed
WO-1998015537-A1 SUBSTITUTED 2-AMINO-4-ALKYLAMINO-1,3,5-TRIAZINES AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-04-16 WO disclosed
EP-0114374-B1 SUBSTITUTED 4-AMINOMETHYLENE CHROMANS OR CHROMENES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES BAYER AG (DE) 1986-07-23 EP disclosed
US-4563458-A CIRCULATORY SYSTEM DISORDERS BAYER AKTIENGESELLSCHAFT (DE) 1986-01-07 US disclosed
EP-0114374-A1 Substituted 4-aminomethylene chromans or chromenes, process for their preparation and their use in medicines BAYER AG (DE) 1984-08-01 EP disclosed
US-4395410-A Quaternary ammonium antiarrhythmic drugs ELI LILLY AND COMPANY (US) 1983-07-26 US disclosed
EP-0002604-B1 QUATERNARY AMMONIUM SALTS, AND THEIR FORMULATIONS AND PREPARATION ELI LILLY AND COMPANY (US) 1983-05-04 EP disclosed
US-4289787-A PROLONG ACTION POTENTIAL OF CARDIAC TISSUE ELI LILLY AND COMPANY (US) 1981-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220194969-A1 METAL HALIDE PEROVSKITE LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME HCN4, SLC46A1, FES ANPEP 3505/4885ERAP1 4167/4885ERAP2 3831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.