SCHEMBL4895993

SCHEMBL4895993

NC(Cc1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.68
ALPI P09923 1/20 0.68
PKM P14618 1/20 0.68
PTGS1 P23219 1/20 0.68
XIAP P98170 1/20 0.68
MDM2 Q00987 1/20 0.66
SLC15A1 P46059 1/20 0.58
LTA4H P09960 1/20 0.54
SLC1A3 P43003 2/20 0.53
SLC1A2 P43004 2/20 0.53
SLC1A1 P43005 2/20 0.53
HDAC8 Q9BY41 2/20 0.51
EPHX1 P07099 1/20 0.50
CYP1A2 P05177 1/20 0.50
CTSC P53634 1/20 0.49
LAP3 P28838 3/20 0.48
ANPEP P15144 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3136979 1.00 SLC7A5 (0.68) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL6347054 0.98 SLC7A5 (0.66) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL10339601 0.98 SLC7A5 (0.66) SLC7A5ALPIPKMPTGS1XIAP
Alanine SCHEMBL28123996 0.91 SLC7A5 (0.62) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL3657476 0.88 SLC7A5 (0.53) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL1249125 0.86 SLC7A5 (0.51) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL23159186 0.81 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL8118 0.81 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL16398197 0.81 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL385804 0.81 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113387768-A Separation method of five fractions of cracked carbon 景利娟 2021-09-14 CN claimed
US-4283434-A FOR FOODS NUTRASWEET COMPANY THE 1981-08-11 US claimed
CN-111763164-B Preparation method and application of ortho-carbonyl amino substituted benzene derivatives 中国医学科学院药物研究所 2023-03-10 CN disclosed
CN-112851536-B Method for constructing amide bond by clicking pyrimidine condensing agent and application of method in amide and polypeptide synthesis 兰州大学 2022-02-25 CN disclosed
CN-113387768-A Separation method of five fractions of cracked carbon 景利娟 2021-09-14 CN disclosed
CN-112851536-A Method for constructing amide bond by clicking pyrimidine condensing agent and application of method in amide and polypeptide synthesis 兰州大学 2021-05-28 CN disclosed
WO-2020130155-A1 HYDROFLUORIC ACID-RESISTANT RESIST COMPOSITION, AND PROCESSED SUBSTRATE PRODUCT PRODUCED USING SAME 太陽インキ製造株式会社 2020-06-25 WO disclosed
US-20080027075-A1 Quaternary Amino-Function Chalcones LICA PHARMACEUTICALS A/S (DK) 2008-01-31 US disclosed
EP-1682486-A1 QUATERNARY AMINO-FUNCTIONAL CHALCONES Lica Pharmaceuticals A/S (DK) 2006-07-26 EP disclosed
US-20060052600-A1 Amino-functional chalcones LICA PHARMACEUTICALS A/S (DK) 2006-03-09 US disclosed
WO-2005042467-A1 QUATERNARY AMINO-FUNCTIONAL CHALCONES LICA PHARMACEUTICALS A/S (DK) 2005-05-12 WO disclosed
EP-1506157-A2 AMINO-FUNCTIONAL CHALCONES Lica Pharmaceuticals A/S (DK) 2005-02-16 EP disclosed
WO-2003097575-A2 AMINO-FUNCTIONAL CHALCONES LICA PHARMACEUTICALS A/S (DK) 2003-11-27 WO disclosed
US-4348333-A β-Ketocarboxyl and phosphonate dihydro-chalcone sweeteners THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1982-09-07 US disclosed
US-4290975-A N-Sulfonyl amine-mediated sulfamation of amines NUTRASWEET COMPANY THE 1981-09-22 US disclosed
US-4283434-A FOR FOODS NUTRASWEET COMPANY THE 1981-08-11 US disclosed
US-4283434-A FOR FOODS NUTRASWEET COMPANY THE 1981-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080027075-A1 Quaternary Amino-Function Chalcones NR2E1, BET1, NR0B1 SLC7A5 419/4885ALPI 3689/4885PKM 4660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.