Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 7/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4895081 | 0.93 | NTRK1 (0.37) | NTRK1KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4905923 | 0.93 | KDM4E (0.40) | CNR1CNR2NTRK1PIK3CAPDE10A | |
| SCHEMBL4906678 | 0.88 | KMT2A (0.42) | CNR1CNR2PIK3CAKMT2A | |
| SCHEMBL4904935 | 0.87 | MEN1 (0.41) | KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL4575789 | 0.87 | NTRK1 (0.39) | CNR1CNR2NTRK1KMT2AMEN1 | |
| SCHEMBL4576410 | 0.87 | MEN1 (0.39) | KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL4907461 | 0.86 | PIK3CA (0.41) | CNR1CNR2PIK3CAKMT2A | |
| SCHEMBL4904776 | 0.86 | MEN1 (0.40) | CNR2KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL16021048 | 0.85 | MEN1 (0.41) | KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL4906357 | 0.85 | KDM4E (0.41) | CNR2NTRK1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214527-A1 | Hiv Integrase Inhibitors | SHIONOGI & CO. LTD (JP) | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214527-A1 | Hiv Integrase Inhibitors | API5, ING2, SAMHD1 | CNR1 4694/4885CNR2 4815/4885NTRK1 4631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.