SCHEMBL4896709

C=C(C)C(=O)OC(CO)COCCC[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C.C=C(C)C(=O)OCC(O)COCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	TSHR	P16473	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL409950	0.87	PRKCA (0.32)	TSHR
SCHEMBL332526	0.87	PRKCA (0.32)	TSHR
SCHEMBL35465	0.86	TSHR (0.41)	TSHR
SCHEMBL331864	0.86	TSHR (0.41)	TSHR
SCHEMBL16852332	0.86	TSHR (0.41)	TSHR
SCHEMBL18176161	0.85	TSHR (0.40)	TSHR
SCHEMBL29815516	0.84	TSHR (0.39)	TSHR
SCHEMBL18176162	0.84	TSHR (0.39)	TSHR
SCHEMBL18176165	0.83	TSHR (0.35)	TSHR
SCHEMBL14942321	0.82	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20080015282-A1	BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS	JOHNSON & JOHNSON VISION CARE, INC.	2008-01-17	—	—	US	claimed