Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 19/20 | 1.00 |
| ▸ | HDAC3 | O15379 | 16/20 | 1.00 |
| ▸ | HDAC4 | P56524 | 16/20 | 1.00 |
| ▸ | HDAC1 | Q13547 | 16/20 | 1.00 |
| ▸ | HDAC7 | Q8WUI4 | 16/20 | 1.00 |
| ▸ | HDAC2 | Q92769 | 16/20 | 1.00 |
| ▸ | HDAC10 | Q969S8 | 16/20 | 1.00 |
| ▸ | HDAC11 | Q96DB2 | 16/20 | 1.00 |
| ▸ | HDAC6 | Q9UBN7 | 16/20 | 1.00 |
| ▸ | HDAC9 | Q9UKV0 | 16/20 | 1.00 |
| ▸ | HDAC5 | Q9UQL6 | 16/20 | 1.00 |
| ▸ | TUBB4A | P04350 | 10/20 | 1.00 |
| ▸ | TUBB | P07437 | 10/20 | 1.00 |
| ▸ | TUBA3C | P0DPH7 | 10/20 | 1.00 |
| ▸ | TUBA1B | P68363 | 10/20 | 1.00 |
| ▸ | TUBA4A | P68366 | 10/20 | 1.00 |
| ▸ | TUBB4B | P68371 | 10/20 | 1.00 |
| ▸ | TUBB3 | Q13509 | 10/20 | 1.00 |
| ▸ | TUBB2A | Q13885 | 10/20 | 1.00 |
| ▸ | TUBB8 | Q3ZCM7 | 10/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2144150 | 0.88 | HDAC8 (1.00) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2143790 | 0.88 | HDAC8 (1.00) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1367877 | 0.88 | HDAC8 (1.00) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4886993 | 0.85 | HDAC8 (1.00) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4896867 | 0.80 | HDAC8 (1.00) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4899333 | 0.80 | HDAC8 (1.00) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4896687 | 0.79 | HDAC8 (1.00) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL17425318 | 0.76 | HDAC8 (0.77) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30304758 | 0.76 | HDAC8 (1.00) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14862921 | 0.76 | HDAC8 (1.00) | HDAC8HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275023-A1 | N-Hydroxyamides Omege-Substituted with Tricyclic Groups as Histone Deacetylase Inhibitors, Their Preparation and Use in Pharmaceutical Formulations | MENARIN INTERNATIONAL OPERATIONS LUXEMBOURG S.A. (LU) | 2008-11-06 | — | — | US | claimed |
| US-20080275023-A1 | N-Hydroxyamides Omege-Substituted with Tricyclic Groups as Histone Deacetylase Inhibitors, Their Preparation and Use in Pharmaceutical Formulations | MENARIN INTERNATIONAL OPERATIONS LUXEMBOURG S.A. (LU) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275023-A1 | N-Hydroxyamides Omege-Substituted with Tricyclic Groups as Histone Deacetylase Inhibitors, Their Preparation and Use in Pharmaceutical Formulations | HDAC8, HDAC2, HDAC7 | HDAC8 1/4885HDAC3 5/4885HDAC4 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.