SCHEMBL4897111

SCHEMBL4897111

CCCCCCCCCCCCCCCCCC(=O)Nc1cc2cccnc2c2ncccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 5/20 0.54
HDAC3 O15379 3/20 0.54
HDAC4 P56524 3/20 0.54
HDAC1 Q13547 3/20 0.54
HDAC7 Q8WUI4 3/20 0.54
HDAC2 Q92769 3/20 0.54
HDAC10 Q969S8 3/20 0.54
HDAC11 Q96DB2 3/20 0.54
HDAC8 Q9BY41 3/20 0.54
HDAC9 Q9UKV0 3/20 0.54
HDAC5 Q9UQL6 3/20 0.54
KDM4E B2RXH2 2/20 0.53
ALDH1A1 P00352 2/20 0.53
GAA P10253 2/20 0.53
HPGD P15428 2/20 0.53
TSHR P16473 2/20 0.53
HSD17B10 Q99714 2/20 0.53
GLA P06280 1/20 0.53
MAPK1 P28482 1/20 0.53
EP300 Q09472 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18788282 1.00 HDAC6 (0.54) HDAC6HDAC3HDAC4HDAC1HDAC7
SCHEMBL30231911 1.00 HDAC6 (0.54) HDAC6HDAC3HDAC4HDAC1HDAC7
SCHEMBL18788301 1.00 HDAC6 (0.54) HDAC6HDAC3HDAC4HDAC1HDAC7
SCHEMBL18788303 1.00 HDAC6 (0.54) HDAC6HDAC3HDAC4HDAC1HDAC7
SCHEMBL15444290 1.00 HDAC6 (0.54) HDAC6HDAC3HDAC4HDAC1HDAC7
SCHEMBL18788311 0.99 KDM4E (0.54) HDAC6HDAC3HDAC4HDAC1HDAC7
SCHEMBL18788266 0.95 ALDH1A1 (0.53) HDAC6HDAC3HDAC4HDAC1HDAC7
SCHEMBL18788344 0.91 GSK3A (0.52) HDAC6HDAC3HDAC4HDAC1HDAC7
SCHEMBL13923686 0.90 HDAC6 (0.53) HDAC6HDAC3HDAC4HDAC1HDAC7
SCHEMBL3193915 0.89 HTT (0.64) HDAC6HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8986436-B2 Luminescent pigments and their use in security applications Fábrica Nacional de Moneda y Timbre—Real Casa de la Moneda (ES) 2015-03-24 US claimed
EP-2673335-B1 LUMINESCENT PIGMENTS AND THEIR USE IN SECURITY APPLICATIONS FÁBRICA NAC DE MONEDA Y TIMBRE REAL CASA DE LA MONEDA (ES) 2014-12-10 EP claimed
US-20140158019-A1 LUMINESCENT PIGMENTS AND THEIR USE IN SECURITY APPLICATIONS FABRICA NAIONAL DE MONEDA Y TIMBRE- REAL CASA DE LA MONEDA (ES) 2014-06-12 US claimed
US-9193746-B2 Luminescent metal complexes and associated technology BIOTIUM, INC. (US) 2015-11-24 US disclosed
US-8986436-B2 Luminescent pigments and their use in security applications Fábrica Nacional de Moneda y Timbre—Real Casa de la Moneda (ES) 2015-03-24 US disclosed
EP-2673335-B1 LUMINESCENT PIGMENTS AND THEIR USE IN SECURITY APPLICATIONS FÁBRICA NAC DE MONEDA Y TIMBRE REAL CASA DE LA MONEDA (ES) 2014-12-10 EP disclosed
US-20140158019-A1 LUMINESCENT PIGMENTS AND THEIR USE IN SECURITY APPLICATIONS FABRICA NAIONAL DE MONEDA Y TIMBRE- REAL CASA DE LA MONEDA (ES) 2014-06-12 US disclosed
US-20080145526-A1 Luminescent Metal Complexes and Associated Technology BIOTIUM, INC. 2008-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080145526-A1 Luminescent Metal Complexes and Associated Technology CLTA, CLTB, CACYBP HDAC6 2835/4885HDAC3 3560/4885HDAC4 4419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.