Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Thiophene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiophene SCHEMBL4897121 | 1.00 | — | — | |
| Thiophene SCHEMBL27926242 | 1.00 | — | — | |
| Thiophene SCHEMBL28371819 | 1.00 | — | — | |
| Thiophene SCHEMBL623718 | 1.00 | — | — | |
| Thiophene SCHEMBL25248961 | 0.95 | — | — | |
| Bromide SCHEMBL9648369 | 0.95 | TP53 (0.30) | — | |
| Thiophene SCHEMBL28074708 | 0.95 | — | — | |
| Thiophene SCHEMBL3805322 | 0.95 | — | — | |
| Thiophene SCHEMBL168628 | 0.94 | — | — | |
| Thiophene SCHEMBL225198 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114316216-B | Symmetrical polymer based on dithieno quinoxaline matrix as center and flexible electrochromic device | 厦门华厦学院 | 2023-07-07 | — | — | CN | claimed |
| CN-113278015-B | Fluorescent probe and preparation method and application thereof | 云南大学 | 2022-05-13 | — | — | CN | claimed |
| CN-113278015-A | Fluorescent probe and preparation method and application thereof | 云南大学 | 2021-08-20 | — | — | CN | claimed |
| CN-114316216-B | Symmetrical polymer based on dithieno quinoxaline matrix as center and flexible electrochromic device | 厦门华厦学院 | 2023-07-07 | — | — | CN | disclosed |
| CN-113278015-B | Fluorescent probe and preparation method and application thereof | 云南大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-113278015-A | Fluorescent probe and preparation method and application thereof | 云南大学 | 2021-08-20 | — | — | CN | disclosed |
| CN-103477460-B | Conjugated polymer | 默克专利股份有限公司 | 2016-11-23 | — | — | CN | disclosed |
| CN-103842402-A | Conjugated polymers | MERCK PATENT GMBH | 2014-06-04 | — | — | CN | disclosed |
| CN-103477460-A | Conjugated polymers | MERCK PATENT GMBH | 2013-12-25 | — | — | CN | disclosed |
| US-8541541-B2 | Polythiophene, polyaniline, polypyrrol, a methacrylic polymer, copolymer or terpolymer, polyamides, and ethylenically unsaturated copolymerizable monomers other than methylmethacrylate; using a controlled radical polymerization initiator of an alkoxyamine | ARKEMA INC. (US) | 2013-09-24 | — | — | US | disclosed |
| EP-1882001-B1 | CONDUCTIVE BLOCK COPOLYMERS, METHODS AND ARTICLES | ARKEMA INC (US) | 2013-01-02 | — | — | EP | disclosed |
| US-20080169451-A1 | Conductive Block Copolymers | ARKEMA INC. (US) | 2008-07-17 | — | — | US | disclosed |
| EP-1882001-A2 | CONDUCTIVE BLOCK COPOLYMERS | Arkema Inc. (US) | 2008-01-30 | — | — | EP | disclosed |
| WO-2006096550-A2 | CONDUCTIVE BLOCK COPOLYMERS | ARKEMA INC. (US) | 2006-09-14 | — | — | WO | disclosed |