Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 16/20 | 0.68 |
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4897336 | 1.00 | CNR1 (0.68) | CNR1KDM1ASCN9A | |
| SCHEMBL4923167 | 0.92 | CNR1 (0.57) | CNR1SCN9A | |
| SCHEMBL4637589 | 0.91 | CNR1 (0.69) | CNR1KDM1ASCN9A | |
| SCHEMBL4897771 | 0.88 | CNR1 (0.69) | CNR1KDM1A | |
| SCHEMBL4603501 | 0.87 | CNR1 (0.56) | CNR1KDM1A | |
| SCHEMBL4897033 | 0.86 | CNR1 (0.58) | CNR1KDM1A | |
| SCHEMBL4915234 | 0.85 | CNR1 (0.58) | CNR1KDM1A | |
| SCHEMBL4915199 | 0.83 | CNR1 (0.58) | CNR1SCN9A | |
| SCHEMBL4886166 | 0.82 | CNR1 (0.52) | CNR1SCN9A | |
| SCHEMBL4886146 | 0.82 | CNR1 (0.52) | CNR1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306115-A1 | Midazole-4-Carboxamide Derivatives For Use As Cb1 Modulators | ASTRAZENECA AB (SE) | 2008-12-11 | — | — | US | claimed |
| US-20080306115-A1 | Midazole-4-Carboxamide Derivatives For Use As Cb1 Modulators | ASTRAZENECA AB (SE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306115-A1 | Midazole-4-Carboxamide Derivatives For Use As Cb1 Modulators | CNR2, CNR1, FAAH | CNR1 2/4885KDM1A 864/4885SCN9A 922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.