Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 5/20 | 0.49 |
| ▸ | PPARA | Q07869 | 4/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4895944 | 0.88 | SMN1; SMN2 (0.55) | SMN1; SMN2PPARGPPARAFOLH1KMT2A | |
| SCHEMBL5010216 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2PPARGPPARAHPGDL3MBTL1 | |
| SCHEMBL2556069 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2PPARGPPARAFOLH1KMT2A | |
| SCHEMBL30530857 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2PPARGPPARAFOLH1KMT2A | |
| SCHEMBL7117920 | 0.81 | PRSS1 (0.55) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL19707956 | 0.81 | PDE4A (0.51) | SMN1; SMN2KMT2ATHRATHRB | |
| SCHEMBL15199284 | 0.80 | FOLH1 (0.56) | PPARGPPARAFOLH1THRATHRB | |
| SCHEMBL4891913 | 0.80 | ESR1 (0.56) | SMN1; SMN2PPARGPPARAFOLH1 | |
| SCHEMBL11463053 | 0.79 | ERCC5 (0.63) | SMN1; SMN2KMT2ATHRATHRBHPGD | |
| SCHEMBL4637827 | 0.79 | CES2 (0.62) | SMN1; SMN2KMT2AHPGDHTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255078-A1 | Triphenylethylene Compounds Useful as Selective Estrogen Receptor Modulators | KATAMREDDY SUBBA REDDY | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255078-A1 | Triphenylethylene Compounds Useful as Selective Estrogen Receptor Modulators | GPER1, ESR2, ESRRG | SMN1; SMN2 4741/4885PPARG 63/4885PPARA 161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.