SCHEMBL4897942

SCHEMBL4897942

CCCCCCCCCCCCCCCC(C)n1ccnc1CC[Si](OC)(OC)OC

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
ADA P00813 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP2C19 P33261 1/20 0.33
TLR7 Q9NYK1 2/20 0.33
HTR2A P28223 1/20 0.32
HTR1A P08908 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4899771 1.00 LMNA (0.33) LMNAADASMN1; SMN2ALDH1A1CYP2C19
SCHEMBL4890731 0.94 LMNA (0.35) LMNAADASMN1; SMN2ALDH1A1CYP2C19
SCHEMBL4897254 0.94 LMNA (0.35) LMNAADASMN1; SMN2ALDH1A1CYP2C19
SCHEMBL4896303 0.89 ADA (0.32) LMNAADASMN1; SMN2ALDH1A1CYP2C19
SCHEMBL4898302 0.89 ADA (0.32) LMNAADASMN1; SMN2ALDH1A1CYP2C19
SCHEMBL4898362 0.87 ADA (0.34) LMNAADASMN1; SMN2ALDH1A1CYP2C19
SCHEMBL4895847 0.87 ADA (0.34) LMNAADASMN1; SMN2ALDH1A1CYP2C19
SCHEMBL4898585 0.82 ADA (0.32) LMNAADASMN1; SMN2ALDH1A1CYP2C19
SCHEMBL4892834 0.82 ADA (0.32) LMNAADASMN1; SMN2ALDH1A1CYP2C19
SCHEMBL4898433 0.79 MC4R (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080274305-A1 Liquid Crystal Sealant and Liquid Crystal Display Cell Utilizing the Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-11-06 US disclosed
EP-1780587-A1 LIQUID CRYSTAL SEALANT AND LIQUID CRYSTAL DISPLAY CELL UTILIZING THE SAME Nippon Kayaku Kabushiki Kaisha (JP) 2007-05-02 EP disclosed