Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.51 |
| ▸ | DRD1 | P21728 | 2/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.51 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL489547 | 0.93 | CACNA1C (0.44) | HTR1AADRA2ACHRM1DRD1TBXA2R | |
| SCHEMBL489902 | 0.93 | TBXA2R (0.51) | HTR1AADRA2ACHRM1DRD1TBXA2R | |
| SCHEMBL489514 | 0.92 | CACNA1C (0.52) | HTR1AADRA2ACHRM1DRD1TBXA2R | |
| SCHEMBL489555 | 0.91 | HTR1A (0.54) | HTR1AADRA2ACHRM1DRD1TBXA2R | |
| SCHEMBL17999035 | 0.90 | HTR1A (0.39) | HTR1AADRA2ACHRM1DRD1TBXA2R | |
| SCHEMBL489785 | 0.89 | CACNA1C (0.44) | HTR1AADRA2ACHRM1DRD1TBXA2R | |
| SCHEMBL489544 | 0.88 | MTOR (0.46) | TBXA2RADRA1ASLC6A3CACNA1CABCB11 | |
| SCHEMBL489559 | 0.87 | CACNA1C (0.44) | HTR1AADRA2ACHRM1DRD1TBXA2R | |
| SCHEMBL489564 | 0.86 | TBXA2R (0.54) | HTR1AADRA2ACHRM1DRD1TBXA2R | |
| SCHEMBL489973 | 0.85 | HTR1A (0.52) | HTR1AADRA2ACHRM1DRD1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106062-B1 | Calcium channel blockers | DIAKRON PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | claimed |
| US-8106062-B1 | Calcium channel blockers | DIAKRON PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | disclosed |