Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.49 |
| ▸ | MECP2 | P51608 | 1/20 | 0.49 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.49 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.49 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.49 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4897056 | 0.84 | SYK (0.47) | RAB9ASYKSRCCDK2ZAP70 | |
| SCHEMBL4904404 | 0.83 | PDPK1 (0.45) | RAB9ANPC1KMT2ASYKMEN1 | |
| SCHEMBL1849187 | 0.82 | SYK (0.62) | SYKSRCCDK2ZAP70HSP90AA1 | |
| SCHEMBL4896690 | 0.82 | SYK (0.49) | RAB9ANPC1KMT2ASYKMEN1 | |
| SCHEMBL4899359 | 0.82 | SYK (0.49) | RAB9ASYKSRCCDK2ZAP70 | |
| SCHEMBL4901358 | 0.82 | SLC2A1 (0.49) | RAB9ANPC1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL27682393 | 0.82 | RAB9A (0.40) | RAB9ASYKSRCCDK2ZAP70 | |
| SCHEMBL4899942 | 0.82 | LYN (0.49) | RAB9ANPC1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL4899975 | 0.82 | RAB9A (0.40) | RAB9AKMT2ALMNASYKMEN1 | |
| SCHEMBL20919346 | 0.82 | KMT2A (0.57) | RAB9AMECP2KCNN1KCNN2MBD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | ICAGEN, INC. (US) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | KCNJ2, KCNH2, KCNQ1 | RAB9A 3132/4885MECP2 2076/4885KCNN1 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.