Sugi Predict

Sugi Predict / Compounds / SCHEMBL4899515

SCHEMBL4899515

SCHEMBL4899515

Cc1ccc(-c2nc(CON=C(Cc3ccccc3)c3ccc(OCC(=O)O)c(C)c3)c(C)o2)cc1

nearest known ligand 0.76

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ PPARG P37231 13/20 0.76
▸ PPARA Q07869 13/20 0.76
▸ PPARD Q03181 6/20 0.76
▸ TP53 P04637 2/20 0.44
▸ POLB P06746 1/20 0.44
▸ CYP2C9 P11712 2/20 0.43
▸ KCNH2 Q12809 2/20 0.43
▸ MAPT P10636 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4729536 1.00 PPARG (0.76) PPARGPPARAPPARDTP53POLB
SCHEMBL4729541 0.93 PPARG (0.72) PPARGPPARAPPARDTP53POLB
SCHEMBL4782933 0.88 PPARG (0.78) PPARGPPARAPPARDTP53POLB
SCHEMBL4727541 0.88 PPARG (0.78) PPARGPPARAPPARDTP53POLB
SCHEMBL4731275 0.87 PPARG (0.79) PPARGPPARAPPARDTP53POLB
SCHEMBL4731269 0.87 PPARG (0.79) PPARGPPARAPPARDTP53POLB
SCHEMBL4726352 0.86 PPARG (1.00) PPARGPPARAPPARDTP53POLB
SCHEMBL4727907 0.86 PPARG (0.56) PPARGPPARAPPARDTP53POLB
SCHEMBL4726309 0.84 PPARG (1.00) PPARGPPARAPPARDMAPT
SCHEMBL4728589 0.84 PPARG (1.00) PPARGPPARAPPARDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 — — WO disclosed