SCHEMBL4727907

SCHEMBL4727907

CCC(Oc1ccc(/C(Cc2ccccc2)=N\OCc2nc(-c3ccc(C)cc3)oc2C)cc1C)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARG P37231 12/20 0.56
PPARA Q07869 9/20 0.56
PPARD Q03181 2/20 0.56
POLB P06746 2/20 0.40
TP53 P04637 2/20 0.40
MAPT P10636 3/20 0.40
THRB P10828 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4727900 0.93 PPARG (0.53) PPARGPPARAPPARDPOLB
SCHEMBL4726339 0.90 PPARG (0.58) PPARGPPARAPPARDPOLBTP53
SCHEMBL4728138 0.88 PPARG (0.58) PPARGPPARAPPARDPOLBTP53
SCHEMBL4728134 0.88 PPARG (0.58) PPARGPPARAPPARDPOLBTP53
SCHEMBL4731237 0.87 PPARG (0.73) PPARGPPARAPPARDPOLBTP53
SCHEMBL4899515 0.86 PPARG (0.76) PPARGPPARAPPARDPOLBTP53
SCHEMBL4729536 0.86 PPARG (0.76) PPARGPPARAPPARDPOLBTP53
SCHEMBL4728569 0.85 PPARG (0.72) PPARGPPARAPPARD
SCHEMBL4728564 0.85 PPARG (0.72) PPARGPPARAPPARD
SCHEMBL4726343 0.84 PPARG (0.53) PPARGPPARAPPARDPOLBTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO claimed
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO disclosed