SCHEMBL49001

SCHEMBL49001

CCCC(CCCO)C(=O)O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.76
AKR1A1 P14550 1/20 0.76
CHRM3 P20309 1/20 0.76
HTR2A P28223 1/20 0.76
HTR2C P28335 1/20 0.76
ADRA1A P35348 1/20 0.76
HRH1 P35367 1/20 0.76
DRD3 P35462 1/20 0.76
SLC6A3 Q01959 1/20 0.76
HDAC1 Q13547 1/20 0.76
HDAC2 Q92769 1/20 0.76
TDP1 Q9NUW8 1/20 0.76
CA2 P00918 2/20 0.58
MAPK1 P28482 1/20 0.58
SLC1A2 P43004 3/20 0.52
SLC1A1 P43005 3/20 0.52
GRIK1 P39086 3/20 0.52
GRIK2 Q13002 3/20 0.52
SLC1A3 P43003 2/20 0.52
CYP3A4 P08684 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17061401 0.98 CHRM1 (0.73) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL676550 0.93 CHRM1 (0.73) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL11000373 0.93 CA2 (0.68) CHRM1AKR1A1CHRM3HTR2AHTR2C
Valproic Acid SCHEMBL11158677 0.93 CHRM1 (0.80) CHRM1AKR1A1CHRM3HTR2AHTR2C
Valproic Acid SCHEMBL11163012 0.93 CHRM1 (0.80) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL8984511 0.91 CHRM1 (0.70) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL5524593 0.91 CHRM1 (0.70) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL3833693 0.91 CHRM1 (0.70) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL5519471 0.91 CHRM1 (0.70) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL3688450 0.91 CHRM1 (0.70) CHRM1AKR1A1CHRM3HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10646832-B2 High selectivity copolyimide membranes for separations UOP LLC 2020-05-12 US claimed
US-20180050309-A1 HIGH SELECTIVITY COPOLYIMIDE MEMBRANES FOR SEPARATIONS UOP LLC 2018-02-22 US claimed
US-9669363-B2 High permeance membranes for gas separations UOP LLC (US) 2017-06-06 US claimed
US-9662616-B2 Aromatic alkyl-substituted polyethersulfone and UV-cross-linked aromatic alkyl-substituted polyethersulfone membranes for gas sepratations UOP LLC (US) 2017-05-30 US claimed
US-9567436-B2 Super high selectivity aromatic block copolyimide membranes for separations UOP LLC (US) 2017-02-14 US claimed
US-20160303521-A1 HIGH PERMEANCE MEMBRANES FOR GAS SEPARATIONS UOP LLC 2016-10-20 US claimed
US-20160279580-A1 AROMATIC ALKYL-SUBSTITUTED POLYETHERSULFONE AND UV-CROSS-LINKED AROMATIC ALKYL-SUBSTITUTED POLYETHERSULFONE MEMBRANES FOR GAS SEPARATIONS UOP LLC 2016-09-29 US claimed
WO-2016100058-A1 SUPER HIGH SELECTIVITY AROMATIC BLOCK COPOLYIMIDE MEMBRANES FOR SEPARATIONS UOP LLC (US) 2016-06-23 WO claimed
US-20160177035-A1 SUPER HIGH SELECTIVITY AROMATIC BLOCK COPOLYIMIDE MEMBRANES FOR SEPARATIONS UOP LLC 2016-06-23 US claimed
US-9308503-B2 Polybenzoxazole membranes from self-cross-linkable aromatic polyimide membranes UOP LLC (US) 2016-04-12 US claimed
US-20090126570-A1 Polymer Functionalized Molecular Sieve/Polymer Mixed Matrix Membranes UOP LLC 2009-05-21 US claimed
US-20090126567-A1 Mixed Matrix Membranes Containing Molecular Sieves With Thin Plate Morphology UOP LLC 2009-05-21 US claimed
US-20090120875-A1 High Performance Mixed Matrix Membranes Incorporating at Least Two Kinds of Molecular Sieves UOP LLC 2009-05-14 US claimed
US-20080295692-A1 UV CROSS-LINKED POLYMER FUNCTIONALIZED MOLECULAR SIEVE/POLYMER MIXED MATRIX MEMBRANES FOR SULFUR REDUCTION UOP LLC 2008-12-04 US claimed
US-20080296527-A1 UV CROSS-LINKED POLYMER FUNCTIONALIZED MOLECULAR SIEVE/POLYMER MIXED MATRIX MEMBRANES UOP LLC 2008-12-04 US claimed
US-20080142440-A1 Liquid Separations Using High Performance Mixed Matrix Membranes UOP LLC 2008-06-19 US claimed
EP-0110955-B1 BRAIN-SPECIFIC DRUG DELIVERY UNIV FLORIDA (US) 1995-08-23 EP claimed
EP-0224283-A2 Brain-specific drug delivery UNIVERSITY OF FLORIDA (US) 1987-06-03 EP claimed
EP-0222425-A2 Brain-specific drug delivery UNIVERSITY OF FLORIDA (US) 1987-05-20 EP claimed
EP-0218300-A2 Brain-specific drug delivery UNIVERSITY OF FLORIDA (US) 1987-04-15 EP claimed