Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4894069 | 0.90 | MAP2K2 (0.33) | MAP2K2MAP2K1FASN | |
| SCHEMBL4891153 | 0.81 | KCNH2 (0.39) | MAP2K2MAP2K1FASN | |
| SCHEMBL8346651 | 0.81 | HSP90B1 (0.32) | — | |
| SCHEMBL4903195 | 0.77 | FASN (0.34) | FASN | |
| SCHEMBL4900444 | 0.77 | MAOB (0.35) | MAP2K2MAP2K1 | |
| SCHEMBL4896839 | 0.72 | HSP90B1 (0.30) | — | |
| SCHEMBL4900824 | 0.71 | KCNH2 (0.40) | MAP2K2MAP2K1 | |
| SCHEMBL4899905 | 0.71 | — | — | |
| SCHEMBL6559757 | 0.70 | TDP1 (0.36) | — | |
| SCHEMBL4900356 | 0.67 | FASN (0.32) | MAP2K2MAP2K1FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132549-A1 | Sulphur-Linked Imidazone Compounds for the Treatment of Hiv/Aids | PFIZER INC. (US) | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132549-A1 | Sulphur-Linked Imidazone Compounds for the Treatment of Hiv/Aids | SPR, TPMT, IMPDH1 | MAP2K2 3967/4885MAP2K1 4066/4885FASN 723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.