Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.50 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.50 |
| ▸ | PPARD | Q03181 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL19462909 | 0.83 | TDP1 (0.93) | TDP1TSHRCYP2C19MAPTPTGDR2 | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL27783 | 0.82 | TDP1 (1.00) | TDP1TSHRCYP2C19MAPTPTGDR2 | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL11716042 | 0.82 | TDP1 (1.00) | TDP1TSHRCYP2C19MAPTPTGDR2 | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL226803 | 0.82 | TDP1 (1.00) | TDP1TSHRCYP2C19MAPTPTGDR2 | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL31108925 | 0.82 | TDP1 (1.00) | TDP1TSHRCYP2C19MAPTPTGDR2 | |
| SCHEMBL4899476 | 0.82 | LMNA (0.64) | TDP1TSHRCYP2C19MAPTPTGDR2 | |
| SCHEMBL3534775 | 0.81 | TDP1 (0.68) | TDP1TSHRCYP2C19MAPTPTGDR2 | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL4586671 | 0.81 | TDP1 (0.96) | TDP1TSHRCYP2C19MAPTPTGDR2 | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL7618485 | 0.81 | TDP1 (0.96) | TDP1TSHRCYP2C19MAPTPTGDR2 | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL17891942 | 0.81 | TDP1 (0.96) | TDP1TSHRCYP2C19MAPTPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006078698-A1 | 2-IMIDAZOLONE AND 2-IMIDAZOLIDINONE HETEROCYCLIC INHIBITORS OF TYROSINE PHOSPHATASES | CENGENT THERAPEUTICS, INC. (US) | 2006-07-27 | — | — | WO | claimed |
| US-20080070867-A1 | 2-Imidazolone and 2-Imidazolidinone Heterocyclic Inhibitors of Tyrosine Phosphatases | METABASIS THERAPEUTICS, INC. (US) | 2008-03-20 | — | — | US | disclosed |
| WO-2006078698-A1 | 2-IMIDAZOLONE AND 2-IMIDAZOLIDINONE HETEROCYCLIC INHIBITORS OF TYROSINE PHOSPHATASES | CENGENT THERAPEUTICS, INC. (US) | 2006-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070867-A1 | 2-Imidazolone and 2-Imidazolidinone Heterocyclic Inhibitors of Tyrosine Phosphatases | PPM1B, PPM1D, PTPRS | TDP1 483/4885TSHR 1439/4885CYP2C19 3325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.