Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 16/20 | 0.64 |
| ▸ | ITGB3 | P05106 | 14/20 | 0.64 |
| ▸ | ITGB1 | P05556 | 12/20 | 0.64 |
| ▸ | ITGA5 | P08648 | 12/20 | 0.64 |
| ▸ | ITGB6 | P18564 | 4/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4904655 | 0.81 | ITGAV (0.68) | ITGAVITGB3ITGB1ITGA5ITGB6 | |
| SCHEMBL14270751 | 0.81 | ITGB3 (0.80) | ITGAVITGB3ITGB1ITGA5ITGB6 | |
| SCHEMBL4931046 | 0.80 | ITGB1 (0.83) | ITGAVITGB3ITGB1ITGA5 | |
| SCHEMBL4901233 | 0.80 | ITGB1 (0.65) | ITGAVITGB3ITGB1ITGA5 | |
| SCHEMBL4201436 | 0.79 | ITGB1 (0.87) | ITGAVITGB3ITGB1ITGA5ITGB6 | |
| SCHEMBL4927554 | 0.79 | ITGB1 (0.77) | ITGAVITGB3ITGB1ITGA5ITGA2B | |
| SCHEMBL4903814 | 0.79 | ITGAV (0.68) | ITGAVITGB3ITGB1ITGA5ITGB6 | |
| SCHEMBL4203355 | 0.78 | ITGB1 (0.75) | ITGAVITGB3ITGB1ITGA5PPARG | |
| SCHEMBL4193779 | 0.78 | ITGB1 (0.70) | ITGAVITGB3ITGB1ITGA5ITGA2B | |
| SCHEMBL4929959 | 0.78 | ITGB1 (0.84) | ITGAVITGB3ITGB1ITGA5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080182842-A1 | L-alanine derivatives as a5beta1 antagonists | ASTRAZENECA AB (SE) | 2008-07-31 | — | — | US | claimed |
| US-20080182842-A1 | L-alanine derivatives as a5beta1 antagonists | ASTRAZENECA AB (SE) | 2008-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182842-A1 | L-alanine derivatives as a5beta1 antagonists | ITGB1, ITGA2B, ITGB5 | ITGAV 7/4885ITGB3 10/4885ITGB1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.