SCHEMBL4900860

SCHEMBL4900860

CCn1cc(C)nc1C[Si](OC)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.33
TSHR P16473 2/20 0.31
LMNA P02545 2/20 0.31
HTT P42858 1/20 0.31
ALDH1A1 P00352 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4900813 0.84 CYP19A1 (0.32) CYP19A1ALDH1A1
SCHEMBL4899193 0.83 TSHR (0.33) CYP19A1TSHRLMNAHTTALDH1A1
SCHEMBL4892786 0.80 SPNS2 (0.33) CYP19A1TSHRLMNAHTTALDH1A1
SCHEMBL6855316 0.77 CYP19A1 (0.47) CYP19A1TSHRLMNAHTTALDH1A1
SCHEMBL3835056 0.75 CYP19A1 (0.41) CYP19A1TSHRLMNAHTTALDH1A1
SCHEMBL18754827 0.73 CYP19A1 (0.36) CYP19A1LMNAALDH1A1
SCHEMBL18516701 0.72 CYP19A1 (0.35) CYP19A1ALDH1A1
SCHEMBL4888368 0.71 CYP19A1 (0.31) CYP19A1
SCHEMBL3836054 0.70 CYP19A1 (0.38) CYP19A1TSHRLMNAHTTALDH1A1
SCHEMBL4897020 0.69 ADRA2B (0.38) TSHRLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080274305-A1 Liquid Crystal Sealant and Liquid Crystal Display Cell Utilizing the Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-11-06 US disclosed
EP-1780587-A1 LIQUID CRYSTAL SEALANT AND LIQUID CRYSTAL DISPLAY CELL UTILIZING THE SAME Nippon Kayaku Kabushiki Kaisha (JP) 2007-05-02 EP disclosed
US-6445567-B1 Cap member for electrical double layer capacitor container HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 2002-09-03 US disclosed
US-20020105776-A1 CAP MEMBER FOR ELECTRICAL DOUBLE LAYER CAPACITOR CONTAINER HONDA GIKEN KOGYO KABUSHIKI KAISHA 2002-08-08 US disclosed