Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3128901 | 0.83 | KDM4E (0.43) | WNT3AHSD17B10ADORA3PDGFRBPDGFRA | |
| SCHEMBL4899168 | 0.81 | KARS1 (0.43) | KARS1NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL4899792 | 0.81 | CYP1A2 (0.41) | WNT3AADORA3PDGFRBPDGFRACYP1A2 | |
| SCHEMBL4902879 | 0.79 | KARS1 (0.52) | ALDH1A1CYP1A2CYP3A4KARS1NPC1 | |
| SCHEMBL4901969 | 0.76 | KARS1 (0.40) | ALDH1A1HPGDKDM4EKARS1NPC1 | |
| Hydrochloric Acid SCHEMBL27662763 | 0.75 | KARS1 (0.47) | ALDH1A1POLBCYP3A4KDM4EKARS1 | |
| SCHEMBL4900004 | 0.75 | KARS1 (0.43) | WNT3AKARS1FYN | |
| SCHEMBL4892104 | 0.75 | CYP2E1 (0.41) | HSD17B10ALDH1A1HPGDCYP3A4KDM4E | |
| SCHEMBL4901121 | 0.75 | KARS1 (0.41) | WNT3AHSD17B10ALDH1A1POLBHPGD | |
| SCHEMBL4902892 | 0.74 | KARS1 (0.40) | HSD17B10ALDH1A1POLBHPGDADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | ICAGEN, INC. (US) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | KCNJ2, KCNH2, KCNQ1 | WNT3A 4254/4885HSD17B10 3953/4885ALDH1A1 3179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.