Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 20/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698594 | 0.80 | OPRL1 (0.47) | OPRL1 | |
| SCHEMBL4888844 | 0.74 | OPRL1 (0.46) | OPRL1 | |
| SCHEMBL4697311 | 0.72 | OPRL1 (0.46) | OPRL1 | |
| SCHEMBL4895198 | 0.70 | OPRL1 (0.38) | OPRL1 | |
| SCHEMBL4900315 | 0.67 | OPRL1 (0.40) | OPRL1 | |
| SCHEMBL4977820 | 0.65 | OPRL1 (0.53) | OPRL1 | |
| SCHEMBL4977830 | 0.65 | OPRL1 (0.53) | OPRL1 | |
| SCHEMBL4977792 | 0.61 | OPRL1 (0.48) | OPRL1 | |
| SCHEMBL4977797 | 0.61 | OPRL1 (0.48) | OPRL1 | |
| SCHEMBL4980222 | 0.60 | OPRL1 (0.45) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207665-A1 | Alpha-(Aryl-or Heteroaryl-Methyl)-Beta-Piperidinopropanoic Acid Compounds as Orl-1-Receptor Antagonists | PFIZER INC. | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207665-A1 | Alpha-(Aryl-or Heteroaryl-Methyl)-Beta-Piperidinopropanoic Acid Compounds as Orl-1-Receptor Antagonists | OPRL1, OGFRL1, OPRD1 | OPRL1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.