SCHEMBL4901374

SCHEMBL4901374

CS(=O)(=O)C(F)(F)C(=NOS(=O)(=O)C(F)(F)F)c1cccc2ccccc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.39
NR4A2 P43354 1/20 0.39
NR4A3 Q92570 1/20 0.39
HPGD P15428 3/20 0.36
KDM4E B2RXH2 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
SLC2A1 P11166 2/20 0.35
CDC25B P30305 2/20 0.35
PLK1 P53350 1/20 0.35
POLB P06746 3/20 0.35
KMT2A Q03164 2/20 0.35
GAA P10253 1/20 0.35
ALDH1A1 P00352 2/20 0.34
HTT P42858 1/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4905888 0.87 NR4A1 (0.41) NR4A1NR4A2NR4A3HPGDKDM4E
SCHEMBL4903336 0.84 NR4A1 (0.41) NR4A1NR4A2NR4A3HPGDKDM4E
SCHEMBL4899498 0.82 MAPT (0.40) NR4A1NR4A2NR4A3HPGDKDM4E
SCHEMBL4901241 0.82 NR4A1 (0.36) NR4A1NR4A2NR4A3HPGDKDM4E
SCHEMBL4903531 0.81 NR4A1 (0.38) NR4A1NR4A2NR4A3HPGDKDM4E
SCHEMBL4903405 0.81 KMT2A (0.37) NR4A1NR4A2NR4A3HPGDKDM4E
SCHEMBL4905976 0.80 NR4A1 (0.36) NR4A1NR4A2NR4A3HPGDKDM4E
SCHEMBL546134 0.79 NR4A1 (0.39) NR4A1NR4A2NR4A3HPGDKDM4E
SCHEMBL546135 0.79 NR4A1 (0.39) NR4A1NR4A2NR4A3HPGDKDM4E
SCHEMBL24397091 0.75 NR4A1 (0.42) NR4A1NR4A2NR4A3HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US claimed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US claimed
US-20080187859-A1 Radiation-Sensitive Resin Composition JSR CORPORATION (JP) 2008-08-07 US disclosed
US-20070269735-A1 Radiation-Sensitive Resin Composition JSR CORPORATION (JP) 2007-11-22 US disclosed
US-7297461-B2 Radiation sensitive resin composition JSR CORPORATION (JP) 2007-11-20 US disclosed
EP-1736829-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-12-27 EP disclosed
EP-1726608-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-11-29 EP disclosed
US-20050171226-A1 Radiation sensitive resin composition JSR CORPORATION (JP) 2005-08-04 US disclosed
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US disclosed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US disclosed