Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 8/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40173 | 0.97 | — | — | |
| SCHEMBL2772577 | 0.97 | CXCR4 (0.44) | CXCR4CA2CHKAKDM4EHRH1 | |
| SCHEMBL272114 | 0.97 | — | — | |
| Piperazine SCHEMBL7550059 | 0.94 | CXCR4 (0.48) | CXCR4PHGDHSMN1; SMN2ALDH1A1TDP1 | |
| Iodide SCHEMBL9066882 | 0.94 | — | — | |
| SCHEMBL18851815 | 0.94 | CXCR4 (0.43) | CXCR4CA2CHKAKDM4EPHGDH | |
| SCHEMBL6632282 | 0.94 | — | — | |
| SCHEMBL18828511 | 0.94 | CXCR4 (0.43) | CXCR4CA2CHKAKDM4EPHGDH | |
| Hydrochloric Acid SCHEMBL22341586 | 0.94 | CXCR4 (0.43) | CXCR4PHGDHSMN1; SMN2ALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL7813671 | 0.94 | CXCR4 (0.43) | CXCR4PHGDHSMN1; SMN2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207157-B2 | agents result in masking attractive odors from insects that normally would be receptive to the attractants by producing anosmia or hyposmia in the insects; ticks, mites, cockroaches and mosquitoes | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2012-06-26 | — | — | US | disclosed |
| US-20080188456-A1 | Methods and Compositions For Repelling Arthropods | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188456-A1 | Methods and Compositions For Repelling Arthropods | HRH4, CHRM5, OPRM1 | CXCR4 58/4885CA2 1684/4885CHKA 3007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.