Cyclopropane

Cyclopropane

SCHEMBL4902095

C1CC1.C1CN1.CCO[SiH](OCC)OCC

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Azepane SCHEMBL554719 0.95 ALDH1A1 (0.45) ALDH1A1
Pyrrolidine SCHEMBL2796382 0.92 ALDH1A1 (0.40) ALDH1A1
Piperazine SCHEMBL27891323 0.92 HIF1A (0.35)
Azetidine SCHEMBL555258 0.92 CXCR4 (0.30) ALDH1A1
Cyclopropane SCHEMBL183646 0.88
SCHEMBL29105471 0.88
Cyclooctane SCHEMBL28671573 0.88
Cyclohexane SCHEMBL28994879 0.88
SCHEMBL1524356 0.88
Ammonia Solution, Strong SCHEMBL11152078 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080041272-A1 Scratch Resistant Gradient Coating and Coated Articles TOMASINO CHARLES 2008-02-21 US disclosed
US-7264669-B1 Scratch resistant gradient coating and coated articles TRIBOFILM RESEARCH, INC. (US) 2007-09-04 US disclosed
EP-0419669-B1 THERMOSETTING COMPOSITION KANEGAFUCHI CHEMICAL IND (JP) 1997-07-09 EP disclosed
US-5639825-A COMPRISING HYDROXYL-CONTAINING RESIN, HYDROLYZABLE SILYL GROUP-CONTAINING RESIN REACTIVE WITH HYDROXYLS, ALKYL SILICATE OR CONDENSATE, AND CURING CATALYST; HARDNESS, SOLVENT RESISTANCE, COATINGS KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1997-06-17 US disclosed
EP-0396914-B1 Coated material KANEGAFUCHI CHEMICAL IND (JP) 1996-01-03 EP disclosed
EP-0400303-B1 Thermosetting composition KANEGAFUCHI CHEMICAL IND (JP) 1995-09-20 EP disclosed
US-5344880-A Hydroxy acrylic resins, acrylic copolymers with alkoxysilane groups, polyorganosiloxane and curing catalysts KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1994-09-06 US disclosed
US-5063114-A Weatherproof, acid and light resistant KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-11-05 US disclosed
EP-0419669-A1 THERMOSETTING COMPOSITION KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-04-03 EP disclosed
EP-0400303-A1 Thermosetting composition KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-12-05 EP disclosed