Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3997959 | 0.94 | FDPS (0.44) | FDPSTSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL28865601 | 0.92 | SMPD1 (0.46) | FDPSTSHRSMPD1ALOX15ALDH1A1 | |
| SCHEMBL28283891 | 0.92 | SMPD1 (0.46) | FDPSTSHRSMPD1ALOX15ALDH1A1 | |
| SCHEMBL4905241 | 0.86 | TSHR (0.42) | FDPSTSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL2201929 | 0.86 | TSHR (0.46) | TSHRCYP2D6CYP2C19HIF1AAKR1B1 | |
| SCHEMBL9175772 | 0.84 | TSHR (0.44) | TSHRCYP2D6CYP2C19HIF1AAKR1B1 | |
| SCHEMBL9178193 | 0.84 | TSHR (0.44) | TSHRCYP2D6CYP2C19HIF1AAKR1B1 | |
| SCHEMBL9179888 | 0.84 | TSHR (0.44) | TSHRCYP2D6CYP2C19HIF1AAKR1B1 | |
| SCHEMBL9344567 | 0.82 | TSHR (0.42) | TSHRCYP2D6CYP2C19HIF1AAKR1B1 | |
| SCHEMBL11596995 | 0.82 | TSHR (0.42) | TSHRCYP2D6CYP2C19HIF1AAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6894082-B2 | Foamable compositions | HENKEL CORPORATION (US) | 2005-05-17 | — | — | US | claimed |
| US-20040063800-A1 | Foamable compositions | HENKEL LOCTITE CORPORATION | 2004-04-01 | — | — | US | claimed |
| WO-2004024807-A1 | FOAMABLE COMPOSITIONS | HENKEL CORPORATION (US) | 2004-03-25 | — | — | WO | claimed |
| US-20080003288-A1 | Responsive microgel and methods related thereto | SUPRATEK PHARMA INC. (CA) | 2008-01-03 | — | — | US | disclosed |
| US-7204997-B2 | Responsive microgel and methods related thereto | SUPRATEK PHARMA INC. (CA) | 2007-04-17 | — | — | US | disclosed |
| US-6894082-B2 | Foamable compositions | HENKEL CORPORATION (US) | 2005-05-17 | — | — | US | disclosed |
| EP-1478403-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA, INC. (CA) | 2004-11-24 | — | — | EP | disclosed |
| US-20040063800-A1 | Foamable compositions | HENKEL LOCTITE CORPORATION | 2004-04-01 | — | — | US | disclosed |
| WO-2004024807-A1 | FOAMABLE COMPOSITIONS | HENKEL CORPORATION (US) | 2004-03-25 | — | — | WO | disclosed |
| WO-2003082940-A1 | FILM ADHESIVES CONTAINING MALEIMIDE AND RELATED COMPOUNDS AND METHODS FOR USE THEREOF | HENKEL CORPORATION (US) | 2003-10-09 | — | — | WO | disclosed |
| US-20030152623-A1 | Responsive microgel and methods related thereto | SUPRATEK PHARMA INC. (CA) | 2003-08-14 | — | — | US | disclosed |
| WO-2003063909-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA INC. (US) | 2003-08-07 | — | — | WO | disclosed |
| EP-0910351-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0907666-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997049736-A2 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |
| WO-1997049387-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |